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Neuraminidase, a key enzyme responsible for influenza virus propagation, has been used as a template for selective synthesis of small subsets of its own inhibitors from theoretically highly diverse dynamic combinatorial libraries. Alanine transaminase release in hBcl-2 modified hepatocytes was lower compared with controls, which could not be further decreased by inhibition of Fas ligand and granzyme B. One Hundred Cases of Paracentesis of the Tympanic Membrane, with the Results obtained therefrom, and Remarks on the Methods of Operation. An improved technique for the paper electrophoresis of parotid saliva. The Zoster Brief Pain Inventory was used to measure severity of pain and interference with activities of daily living because of pain.

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Autoinjection is easily learned for long-term treatment by patients with moderate vascular disorders or neurogenic dysfunction. Spectral, polarization, and coherence properties of the emission were measured to confirm polariton lasing. Comparison of CT and angiography in assessing resectability of pancreatic carcinoma. Extracts of 4-day high-flow intimas degraded more 35S-methionine-labeled versican than low-flow intimal extracts, and this activity was inhibited by AEBSF, a serine proteinase inhibitor, and a plasmin antibody. Splenic rupture following colonoscopy: report of an unusual case in the absence of underlying splenic disease

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The species composition of bifidobacteria in the fecal specimens did not change significantly throughout the study period. On the contrary, important rim stress concentration was found for large osteochondral defects. Influence of charge variation in the Streptomyces venezuelae alpha-amylase signal peptide on heterologous protein production by Streptomyces lividans. We feel that our data may be relevant for future clinical trials of active immunotherapy using tumor lysate-pulsed DCs in patients with MTC who have residual or distant disease after surgical treatment.

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Initial audiologic assessment of infants referred from well baby, special care, and neonatal intensive care unit nurseries. Human CD38 and CD16 are functionally dependent and physically associated in natural killer cells.

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According to these results, it may be expected that tumours with a VEGF/MIB-1 ratio of 1:6 or less prior to RCX will respond to this therapy. Light scattering was measured in solutions of lens proteins after activation of endogenous calpain 2 and/or Lp82. PET/CT images were evaluated for the presence, size and metabolic activity of hilar and mediastinal lymph nodes and pulmonary lesions. Benefits of additional courses of systemic azithromycin in periodontal therapy.

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One of the consequences of cytokine-orchestrated inflammation after CNS trauma is apoptosis. We have used fluorescence spectroscopy to investigate the binding of gene 32 protein from bacteriophage T4 to DNA which has been chemically modified with carcinogens or antitumor drugs. If the target cell of AIDS is the mature T cell as suspected, the methods used in these studies may prove useful for the long-term growth of these cells and for the identification of antigens specific for the etiological agent of AIDS. Incidence and clinical significance of peripheral and bone marrow basophilia.

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Origin, originality, functions, subversions and molecular signalling of macropinocytosis. These findings have implications for the design of improved inhibitors of MbtI, as well as other chorismate-utilizing enzymes from this family.

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Coherent dynamics and association networks among lake bacterioplankton taxa. Hepatobiliary transporters are down-regulated in toxic and cholestatic liver injury. The development of the dorsal and ventral mammalian pancreas in vivo and in vitro. Neuroferritinopathy in a French family with late onset dominant dystonia. Furthermore, our study aimed to find out whether n-6 long chain polyunsaturated fatty acids from linoleic acid are formed in RGM-1 cells.

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The first case exhibited adenocarcinoma of the stomach with metastases to the neck lymph nodes and pancreatic polypeptide hypersecretion. Mechanism for reduced drug clearance in patients with cirrhosis. The GABA level in mouse brain was increased by the administration of AOAA, VPA, DMP and DMP-Cl.

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Characteristics of uterine blood circulation in the puerperium according to clinical-rheographic data Effect of estrogen versus testosterone on circulating osteoprotegerin and other cytokine levels in normal elderly men. Aggregation was initiated by the interaction of EATC with a component(s) of human plasma, possibly related to the complement system, which led to the release of cellular ADP, a potent platelet aggregating agent.

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The 8p11 myeloproliferative syndrome: a distinct clinical entity caused by constitutive activation of FGFR1. Successful thrombolytic therapy of pulmonary embolism associated with urosepsis in an infant. There were no significant differences for NMP22 levels between each different point of time studied. Phase I and pharmacokinetic study of two sequences of gemcitabine and docetaxel administered weekly to patients with advanced cancer. The objective of this study was to provide a systematic review of the current understanding of axial pain after cervical laminoplasty and laminectomy, and summarize clinical features, influence factors and preventive measures of axial pain after posterior decompressive surgery based on a review of literature published in the English language.

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Within the limits of this study, neither maternal iron deficiency nor Fe-overload as measured at term appeared to affect the complement of Fe received by the foetus. The average volume of tumors treated with RAPN was 2.17 cm, 1.98 cm, and 2.78 cm in the first, second, and third half-year, respectively. We further showed that on a blood agar culture plate in the presence of penicillin G, a beta-lactamase positive strain of Staphylococcus aureus allowed growth of Streptococcus pneumoniae. The optimized Tag-primer nested/multiplex PCR shows high sensitivity, specificity and stability in malaria diagnosis.

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Here, we demonstrate the use of this multiplex Pyrosequencing for single nucleotide polymorphisms genotyping and microbial typing. The safety and efficacy of nifurtimox and benznidazole should be compared to improve current therapeutic recommendations, and pharmacovigilance systems should be enhanced. The presence of this mutation, designated uvrD210, increased the frequency of recombination between chromosomal duplications in F-prime repliconant cells and reduced linkage between closely linked markers in crosses with Hfr donors. A longitudinal study of small-for-gestational-age births: prenatal risk factors, newborn characteristics and infant growth and development.

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After controlling for autologous donation, the average hemoglobin level on postoperative day one in the treatment group (10.93 g/dL) was significantly higher than the matched patient group (9.86 g/dL). Detection of Chlamydia trachomatis intrauterine infection using polymerase chain reaction on chorionic villi. This paper focuses on fertility in male and female adult patients with CAH. Our results suggest that shRNA against hTERT mRNA inhibits telomerase activity and cell viability through suppression of the hTERT expression in cancer cells. From January 2000 to June 2002, 42 consecutive, unselected patients who successfully underwent LIHR were matched with 49 consecutive, unselected patients who received OR during the same period.

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We administered a survey to define current transfusion practices for CTT and performed a review of the erythrocytapheresis literature. We studied the extent of multiple paternity in a gastropod with internal fertilization, the intertidal snail Littorina saxatilis. We describe the methods developed for determining the kinetic parameters of an enzyme, such as K(m) and k(cat), and the procedures for inhibitor mechanistic studies including ATP competitiveness and slow-binding and dissociation kinetics. The binding can be disrupted by amino acid substitutions at conserved residues of PR, suggesting that binding is specific.

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Observation of neural electrophysiology and morphology in traumatic optic neuropathy in cat model This may be unrelated to treatment modality, number of sessions or severity of depression. Thermally induced polytype transformations among the layered double hydroxides (LDHs) of Mg and Zn with Al. Maintenance of the lateral localization of CEACAM1-L required homophilic binding between CEACAM1-L molecules on adjacent cells.

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Engaging rural communities in health care through a paramedic expanded scope of practice. The device was extensively tested, and in an ongoing randomized controlled study it is being investigated whether this management strategy is able to hasten the ventilator adaptation process and to diminish the overall utilization of health services, with concurrent economic viability. Radical vulvectomy with bilateral inguinal, femoral, and iliac node resection. Polyethylenimine (PEI) is toxic although it is one of the most successful and widely used gene delivery polymers with the aid of the proton sponge effect. We present a patient with Brugada syndrome in whom 12-lead ECGs were recorded just before and after an episode of ventricular fibrillation (VF).

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Techniques for evaluating the fetus for abnormality including amniocentesis, CVS, ultrasound, percutaneous umbilical blood sampling, fetal biopsy, amniotic fluid alpha-fetoprotein analysis, and maternal serum screening are described. Diagnostic imaging by energetic radioactive particle beams: applications in Bragg Peak cancer therapy. Cytokine requirements for the growth and development of mouse NK cells in vitro. Salmonella cytotoxin present in cell-free sonic lysates causes rounding and detachment of Chinese hamster ovary (CHO) cells.

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Two hundred and eighty patients underwent IVU for suspected ureteral disorders, which identified a definite diagnosis in 184 cases and was insufficient for definite diagnosis in 96 cases designated as indeterminate diagnosis. The effectiveness of adjunctive rehabilitation strategies to improve general functioning deserves additional study. Intravascular morphological manifestations of the syndrome of disseminated intravascular coagulation (DIC) in the acute period of burn disease Surgical treatment of ascending aorta and innominate artery trunk aneurysm with displaced brachiocephalic vessels. Interesting appearance of osseous hemangioma of the calcaneus on bone scintigraphy: correlative imaging with radiography CT and MRI.

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JAG1 is an evolutionarily conserved ligand for Notch receptor and functions in the cell fate decisions, cell-cell interactions throughout the development of heart especially right heart development. Observations concerning blood sedimentation reaction in carcinosis SEE provides effective hemostasis and results in an acceptable depth of necrosis with satisfactory wound healing in a porcine model of solid organ injury.

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Our study investigates whether t-VNS may have the potential to alter pain processing using a controlled design. However, the precise molecular mechanism of macrophage recruitment and activation has not been fully elucidated.

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Measurements of melanoma dimensions by clinical, echographic, and histopathological examinations were compared for 644 eyes. Application of Matrix-assisted Laser Desorption Ionization Time-of-flight Mass Spectrometry for Identification of Coagulase-negative Staphylococci Isolated from Milk of Cows with Subclinical Mastitis. The modulatory effects of FUS on anesthesia suggest potential therapeutic applications for disorders of consciousness such as minimally consciousness states.

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Tissue adenine nucleotides are depleted during cerebral ischemia, impeding recovery after reperfusion. Combining capecitabine and oxaliplatin yields promising activity in advanced colorectal cancer.

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Performance study of the PC-384 positron camera system for emission tomography of the brain. Induction of malignant transformation in vitro and mammary tumors in rats by two new potent anthracycline antitumor antibiotics, morpholinodaunomycin and cyanomorpholinoadriamycin.

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