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Dutasterida (Dutasteride)
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Dutasterida is an analogue of testosterone, and it is a competitive, selective inhibitor of both reproductive (type 2) and skin and hepatic (type 1) 5α-reductase. This results in inhibition of the conversion of testosterone to dihydrotestosterone (DHT) and markedly suppresses serum DHT levels.

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Dutasteride, Deetor, Duodart, Duprost, Dutagen, Dutas, Dutasterida, Dute, Veltride,

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PRKAR1A acts a classic tumor suppressor gene as demonstrated by loss of heterozygosity at the 17q22-24 locus in tumors associated with the complex. Sugar transport in the red blood cell: structure-activity relationships in substrates and antagonists. These multi-drug resistance mechanisms allow bacteria to survive in the presence of clinically useful antimicrobial agents, thus reducing the efficacy of chemotherapy towards infectious disease.

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The results of this pilot study suggest that skin surface microscopy, using a 10x dermoscope, detects purpuric globules in urticarial lesions, and that purpuric globules indicate underlying leucocytoclastic vasculitis. Concomitant hepatic impairment reduced drug clearance, increasing the area under the curve (AUC) per administered milligram of drug, and the Cmax. These findings suggest that 17 beta-estradiol, 17 beta-estradiol 3-glucoside, and 17 beta-estradiol 3-glucuronide are taken up by nuclei by a nonsaturable diffusion process. The performance is not as high as hoped, but the dataset seems to be the main cause. Time-dependent intermolecular interaction during protein reactions.

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This technique is a useful tool for restoration of craniofacial contour in reconstructive head and neck surgery. Recent data have emphasized that a nephrologist can be successfully trained to become a competent interventionalist. Ascites can originate from hepatic, malignant, cardiac, renal, and infectious diseases.

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Quantitative changes in serum protein fractions during the development of kwashiorkor and in recovery. Many different signaling pathways need to be activated concurrently to allow immune-mediated 1alpha-hydroxylase up-regulation.

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Diagnostic and therapeutic procedures in bradyarrhythmias are discussed. The use of carboplatin and paclitaxel in the setting of metastatic salivary gland cancer is a viable option. Therefore, the impact of the difference of the RI(sc) should raise the suspicion for ischemia, and further research is needed to elucidate any effect on spermatogenesis. Does adjuvant radiotherapy increase survival in patients with Merkel cell carcinoma of the skin? A possible role of endogenous inhibitor for nitric oxide synthesis in the bovine ciliary muscle.

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Differentiation-dependent changes in the solubility of a 195-kD protein in human epidermal keratinocytes. Tissue plasminogen activator is also detectable immunocytochemically in lesional psoriatic but not normal epidermis. Since longevity mechanisms can closely correlate to superficial traits, it is unlikely that they comprise an integral part of basic structural or biochemical processes. The lessons learned from the study of infectious intestinal disease in England. Role of Crk-associated substrate in the regulation of vascular smooth muscle contraction.

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Postoperative testing only in a group of 124 patients showed that the development of local tumour recurrence was preceded by significantly greater inhibition of E-rosetting than occurred in patients without recurrence. The level, length, and contour of the strictures were analyzed with endoscopic retrograde cholangiopancreatography (ERCP). These data indicate the value of using Ki-67 to assess the proliferative capacities of the lymphoid cells in cutaneous infiltrates. Myofascial pain of the jaw muscles: comparison of short-term effectiveness of botulinum toxin injections and fascial manipulation technique.

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The ability of Cas to promote migration has been shown to be dependent upon its carboxyl terminus, which contains a bipartite binding site for the protein tyrosine kinase c-Src (Src). The results suggested that the whole-length DegS was able to activate plasminogen on a plasma plate. A wide spectrum of chemical diversity from the modifications provides the ribosome with a broader range of possible interactions between rRNA regions, transfer RNA, messenger RNA, proteins, or ligands by influencing local rRNA folds and fine-tuning the translation process. Differentiating muscle damage from myocardial injury by means of the serum creatine kinase (CK) isoenzyme MB mass measurement/total CK activity ratio. This case demonstrates that despite using careful and accurate technique, it is possible for material to be injected into a radicular artery.

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Roles of intrinsic disorder in protein-nucleic acid interactions. This demonstrated that therapeutic mAbs could be generated a few months after the new virus emerged. Soft tissue cancers: contribution of the anatomo-pathologist to the establishment of the prognosis and therapeutic plan A subgroup of 8 of 25 athletes with menstrual disturbances had significantly higher serum levels of free and total testosterone, androstenedione, LH-FSH ratio, and lower SHBG levels than did all other groups. Follow-up telephone surveys, initiated two weeks later, were completed by 93 women.

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To monitor HIV incidence among homosexually active men seen through a network of sexual health clinics in Australia. Reporting of laboratory-confirmed chlamydial infection and gonorrhea by providers affiliated with three large managed care organizations--United States, 1995-1 999. OmpT is an integral outer membrane protease of Escherichia coli.

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Both soluble fibronectin and lipoteichoic acid inhibited the binding of streptococci to immobilized fibronectin, suggesting that streptococci interact with soluble and insoluble fibronectin in a similar manner. Creating a halo traction wheelchair resource manual: using the EBP approach.

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Polythelia pilosa: a particular form of accessory mammary tissue. Effect of zinc supplementation on type 2 diabetes parameters and liver metallothionein expressions in Wistar rats. Using dual-energy x-ray absorptiometry, we measured total-body BMD and region-of-interest scores for lumbar spine, pelvis, and average leg (average from right and left leg measurements) BMD. An economic and rapid diagnostic procedure for the detection of salmonella/shigella using the polyvalent salmonella phage O-1. Novel sound production through contingency learning in the Pacific walrus (Odobenus rosmarus divergens).

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The CHAMPION PHOENIX is a randomized, double-blind, double-dummy, superiority trial comparing cangrelor with clopidogrel standard of care in approximately 10,900 patients who have not previously received a P2Y(12) inhibitor and who require PCI, including patients with stable angina and with acute coronary syndromes (with or without ST-segment elevation). In the subsequent grasping phase, the scaling of arm raising movement exhibited in the presence of implicit advance knowledge resulted in a reduced need for postural adjustments, particularly at the highest ball speed. Aminopropyl-modified mesoporous silica SBA-15 as recovery agents of Cu(II)-sulfate solutions: Adsorption efficiency, functional stability and reusability aspects. On the contrary, a low degree of pixel colocalization, comparable to that between two unrelated antigens, was detected between SNAP-25 and vGAT, thus suggesting a random overlap of immunofluorescence signals. NPY-IR axon varicosities were juxtaposed to both dendrites and perikarya of the majority of CRH-IR neurons residing in the paraventricular, periventricular, and infundibular nuclei.

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This regulation is determined by phoS gene common to alkaline phosphatase. Similar results were obtained in vivo using a controlled cortical impact model of traumatic injury in mouse brain. Surgical reconstruction of these tendon injuries is complicated by the difficulty in completely neutralizing tensional force across the repair. The chromophore palladium(II) octabutoxynaphthalocyanine (PdNc(OBu)8) accumulates at satisfactory concentrations and with good selectivity between both tumor and muscle and tumor and skin in tumor-bearing mice.

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Tropical forest carbon balance in a warmer world: a critical review spanning microbial- to ecosystem-scale processes. Alcohol intake may be associated with various diseases including cancer. Possible role of corticosteroids in nervous system plasticity: improvement in amblyopia after optic neuritis in the fellow eye treated with steroids. Automated extraction of hepatitis B markers, including quantitative results where available, can help to classify HBV status more accurately for surveillance. Effects of chlordiazepoxide on discriminative fear conditioning and shuttle avoidance performance in the rabbit.

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Leucine-rich repeat kinase 2 (LRRK2) mutations in a Swedish Parkinson cohort and a healthy nonagenarian. Utilization of appropriate analytic strategies is important in the analysis and interpretation of data containing nested structures. A reversed-phase high-performance liquid chromatographic technique was developed to separate cadmium-phytochelatin complexes (Cd-PC2, Cd-PC3, and Cd-PC4) of interest in the plant Arapidopsis thaliana. Simple treatment of meso-bromoporphyrins with sodium azide and sodium ascorbate in DMF affords the corresponding meso-aminoporphyrins in very good yields.

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Regular beta-helices offer new possibilities for the study of protein folding, the production of nanofibers, catalysts, inhibitors of growth factor receptors and drug carriers. A similar regulatory interaction has been defined in Drosophila embryos where Dpp signaling mediated by the Smad homologues Mad and Medea directly regulates early cardiac expression of tinman. A trimodality approach to transitional cell bladder cancer mandates lifelong cystoscopic surveillance. Sodium balance and plasma renin activity during the development of two-kidney Goldblatt hypertension in rats. The substantial neuronal loss which occurs within the right PG after neonatal left HCb lesions is believed to influence the increase in crossed SMP fibers coursing from the right hemisphere to the larger left PG.

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An efficient library construction method was developed by using in vivo recombination in Hansenula polymorpha. The contents of DOPA and catecholamines in several rat tissues and nicotine-induced convulsions. Effect of a dual-purpose inoculant on the quality and nutrient losses from corn silage produced in farm-scale silos. Colloidal particles at a nematic-isotropic interface: effects of confinement.

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Dietary intake data were used to calculate percentage of total energy intake derived from fat, carbohydrate and protein. Direct synovial gene transfer with retroviral vectors in rat adjuvant arthritis.

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The model that included the fewest parameters and that could distinguish tumor recurrence best within 10 years was chosen as the final model. Blood basophils from cystic fibrosis patients with allergic bronchopulmonary aspergillosis are primed and hyper-responsive to stimulation by aspergillus allergens. Patients were subdivided according to the type of disease progression. To examine the rationale for and necessity of adjusting the film focal distance when X-ray angulation is employed during a radiographic study, and to determine the sensitivity of human interpreters to overall differences in film density and the correlation, if any, with digital analysis of radiographic films. Findings of this study demonstrate that craniofacial fibrous dysplasia displays a wide spectrum of clinical behaviors.

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Compactin (ML-236B) reduces the content of filipin-cholesterol complexes in the plasma membrane of chronic lymphocytic leukemia cells. These results are interpreted to mean that a high degree of specificity exists in the organization of electrical coupling among frog lumbar motoneurons. Reducing costs and improving outcomes of percutaneous coronary interventions. Postoperative astigmatism might be reduced in penetrating keratoplasty if surgeons could cut a straight-sided round hole in the recipient cornea and place in that hole a round donor button also having straight sides. Physical and functional interaction between DNA ligase IIIalpha and poly(ADP-Ribose) polymerase 1 in DNA single-strand break repair.

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Photolysis of germane (GeH4) in the presence of acetylene (C2H2), propyne (C3H4) or phosphine (PH3) with a 185 nm mercury lamp has been studied. In this review, we present genetic and molecular models for how these processes work, and summarize the evidence upon which they are built. It transpires that the additional flexibility of an active matching layer can be used to maintain the efficiency of the device as the external load is varied. Polymer E2 also has PEG-FITC conjugated to it, as a model macromolecular drug, and polymer E3 contains a pendant hexalysine moiety for complexing oligonucleotides.

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The inhibitory action of a mammalian viral RNA on the initiation of protein synthesis in a reticulocyte cell-free system. Preovulatory follicles obtained from PMSG-primed rats were cultured for 24 hr in serum-free medium with or without sodium nitroprusside (SNP), a NO generator. 4329 male and 4018 female survivors of childhood cancer who completed a CCSS questionnaire assessing screening and surveillance for new cases of cancer.

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Dyspnoea was measured using a previously validated scale or, in some studies, a simple numerical score. This article reviews clinical and experimental evidence as to whether magnesium sulfate, administered soon before premature birth, can reduce the high rate of cerebral palsy in tiny infants. Age distribution of patients with delirium tremens in Denmark 1836-1978. Extended exposure to simulated weightlessness is followed by significant alterations in the sensory epithelia and also in the otolith membrane.

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Tuberculous retroperitoneal lymphadenopathy mimicking metastatic pancreatic carcinoma. The effects of noradrenaline rezept berliner pfannkuchen im baclofen uses micro-iontophoretically applied on rabbit right atrium pace-maker cells.

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6 cases of calcinosis cutis--with special reference to the mechanisms and route of transepidermal elimination of calcium The functional role of an endosymbiotic conidial fungus (Scopulariopsis brevicaulis) prevalent within the integumental glands and hemocoel of the American dog tick (Dermacentor variabilis) was investigated to explore the nature of this tick/fungus association. The inheritance is autosomal dominant, but there is a considerable number of new mutations. Cop 1 treatment prolonged skin tenvir buy gold graft survival and inhibited the functional deterioration of thyroid grafts, in various strain combinations, across minor and major histocompatibility barriers, similarly to the potent immunosuppressive drug FK506.

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Diagnosis of penicillin allergy by klavox clavulanate potentiated amoxicillin dosage for ear skin testing: the Manitoba experience. Symptomatic appendiceal wall thickening in an HIV-infected patient caused by interleukin-2 therapy.

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