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Topigen (Topiramate)
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Topiramate

Topigen is the brand name used in the United States, Canada, the United Kingdom, Australia, and some other countries for the seizure medicine Topigen (toh-PEER-ah-mate). Topigen is not available in generic (non-brand) form in the United States. There is also an extended release formulation targeted for mid-2013. Topigen is marketed in the United States by Ortho-McNeil Pharmaceuticals. The name or appearance may differ in other countries. The dose (measured in milligrams, abbreviated "mg") will usually be the same.

Other names for this medication:
Topiramate, Topamax, Epitomax, Letop, Neutop, Piramax, Talopam, Topamac, Topictal, Topigen, Topilex, Topimax, Topina, Topiramato, Topirol, Toplep,

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The main conclusion of this research is that imagining an unacceptable, non-consensual act can produce feelings of contamination. Continued follow-up of these patients is required to evaluate oncological outcomes. Late opacification of Hydroview intraocular lens implants is uncommon and aetiology seems to be multifactorial. Chimeric mice developed an abdominal hemorrhage starting 2 to 3 months after transplantation that was ultimately lethal. Lead survey of selected children in Kansas City and some unusual cases.

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The number of BFU-E was significantly increased when donor bone marrow cells were co-cultured with PBMCs obtained from allogeneic marrow recipients in the early post-transplant period. Uterine leiomyomas are the most common benign gynecologic tumors. Use of HLA class II tetramers in tracking antigen-specific T cells and mapping T-cell epitopes. There was no correlation between the dose of methadone and ductal diameter. Transscleral permeability and intraocular concentrations of cisplatin from a collagen matrix.

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Daytime sleepiness and automobile accidents in patients with obstructive sleep apnea syndrome. Significant progress has been made in the development and evaluation of endocrine therapies for systemic adjuvant therapy. Neuronal NOS (nNOS) and DDAH I protein expression were decreased without altering endothelial NOS expression, while arginase I expression was upregulated. Neurovascular syndromes of the shoulder girdle and upper extremity: the compression disorders and the shoulder-hand syndrome. The secondary postoperative increase in insulin can be accounted for by intravenous administration of glucose and, particularly, after pulsatile perfusion, indicates an almost completely normal response of pancreatic beta-cells.

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Some heads were embedded in paraffin while others were put into methyl-methacrylate resin and sections were made. Sunfish were collected from coal ash effluent-receiving streams and Ohio River watershed reference sites to assess the effects of exposure to low-level selenium concentrations. Archived radical prostatectomy specimens obtained from 25 white and 25 black men had AR protein antigen retrieved and immunostained. The purpose of this study was to analyse trends and variations in the secondary sex ratio in Greece during the last 50 years and among different occupational groups of male employees of a shipyard. The differences concerned mainly glutamine, glutamic acid, proline, alanine, glycine.

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Positive-strand RNA viruses build extensive membranous replication compartments to support replication and protect the virus from antiviral responses by the host. Lysis of syngeneic virus-infected cells could not be inhibited by allogeneic target cells. This study aims to investigate the afferent sensory pathways from the anorectum before and during sacral nerve stimulation. Age-specific incidence rates by each site were compared for the Philippines, the United States, and Japan. A novel technique for the internal drainage of extrahepatic biloma complicating transarterial embolization of hepatocellular carcinoma.

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For a base of 47 degrees C, response thresholds of the CMHs ranged from 0.1 to 0.5 degrees C and were comparable to detection thresholds of 0.1 to 0.3 degrees C. To commence use of the term intelligence with regard to plant behaviour will lead to a better understanding of the complexity of plant signal transduction and the discrimination and sensitivity with which plants construct images of their environment, and raises critical questions concerning how plants compute responses at the whole-plant level. The latter would mediate both mitochondrial recognition and autophagosome formation, ultimately leading to removal of damaged mitochondria.

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Two of the tests applied, the Allium and Ames test, revealed the high genotoxicity of leachate 4. A better match between the thermal expansion coefficient of the NCD layer and the underlying substrate results in less stress and a smaller amount of wrinkles as confirmed by Raman spectroscopy and 3D surface imaging.

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Serum levels of vitamin D (25(OH)D), PTH calcium, phosphate (P) and alkaline phosphate were estimated at 2 and 6 weeks, and at 3, 6, 9 and 12 months of age. The fine surface view of the adult human Eustachian tube in normal and pathological conditions.

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There were 15 flaps in 14 male patients in this retrospective study. Conditional acceleration and external disinhibition of operant lever pressing by prereward, neutral, and reinforcing stimuli. We review current literature from the standpoint that intrinsic influences act early in neocortical development to generate molecular patterning whose main role is the guidance of long-range projections from the dorsal thalamus.

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This report underlines the difficulty of the identification of ESBLs in A. The findings supported the significance of the co-construction process within SFBT and the effects of specific types of SFBT techniques. This data may be useful in determining the probability of finding a matched donor and for estimating the incidence of HLA associated diseases. This method relies on the ability to elicit a transient humoral response against the selected endogenous target protein. Acute renal insufficiency in patients with myocardial infarct complicated by cardiogenic shock

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To determine the natural history of colonization with vancomycin-resistant enterococci (VRE), methicillin-resistant Staphylococcus aureus (MRSA), and resistant gram-negative bacilli among long-term-care facility (LTCF) residents. These homeostatic properties of the regulation of sleep-wakefulness are mediated by central adenosinergic modulations. Deforestation is the product of the interactions between environmental, social, economic, cultural, and political forces at work in any given country/region, and thus, more and more attention is focused on the negative socioeconomic and environmental effects after forest degradation, especially on the reduction of forest area induced by deforestation. The ED50 of the complexes NC3, NC4, NC5, and NC6 ranged from 2.2 to 4 times lower than that of nystatin. Such investigations point towards a decreased intensity of reaction to ethanol in sons of alcoholics, a decreased amplitude of the P300 wave of event-related potentials, and the possibility of a unique pattern of waves on the background cortical EEGs.

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The MH is financed with federal, state and county contributions. CT is also very sensitive, and yields detailed information about the location and extent of cystic and other benign lesions. The number of steps per day is not only a parameter allowing a different inside view to daily routines but is also a key for interventional programs. This study found the degree of annoyance related to vehicle exhaust and irritating and asthmatic symptoms to be significantly dependent on the levels of traffic related pollutants outside the home. Nutrition education training of health workers and other field staff to support chronically deprived communities.

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A rapid and simple assay for human blood malignancy engraftment, homing and chemotherapy treatment using fluorescent imaging of avian embryos. Contribution to the study of abnormal piliferous development in the prepuberal stage Efficient mining of genomic sequence information from multiple pathogens for therapeutic and vaccine targets requires efficient tools. To identify clinical manifestations and laboratory findings useful for the early diagnosis of dengue in children.

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A candidate gene for sex determination was localized within a 35 kb region of the Y chromosome immediately adjacent to the pseudoautosomal boundary. Colonoscopic allergen provocation (COLAP): a new diagnostic approach for gastrointestinal food allergy. The suppressive effects of timeout on responding maintained by these schedules were similar to previous reports in which responding was punished with electric shock. Lymphocyte transformation test, reaginic and complement fixing antibodies in guinea pigs sensitized to a metabolite of halothane and fluroxene. Early developing embryos affect the gene expression patterns in the mouse oviduct.

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We present details of a case of intra-tendinous ganglion arising from the long head of the biceps at an unusual location. The fabrication of two all-ceramic crowns fulfilled both functional and esthetic objectives.

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For in vitro study, the oxygen-glucose deprivation(OGD) model was established in H9c2 cells. However, Tpk2 seems to inhibit APC/C function more efficiently than Tpk1 and Tpk3. Expanding our current system will reduce the LOS only in major hospitals, but it will reduce the national average LOS. P-selectin expression peaked after 30 min and could be mimicked with similar kinetics by exposure to L.

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LDL cholesterol levels in diabetics should not exceed 115 mg/dl (3 mmol/l), and fasting triglycerides should be lower than 180 mg/dL (2 mmol/l). Histological and histochemical studies of the placenta and foetal membranes in pathological obsterics. To overcome these problems, we describe two methods to generate a reusable antibody support by cross-linking the antibody to immobilized Protein A or Protein G, or by coupling it directly to the resin (see Scheme 1).

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In this study, the hFIX expression mediated by rAAV8 injected intramuscularly was compared with that by rAAV1. Our knowledge about envelope virus budding has been dramatically increased, since L-domain motifs were identified within their matrix and retroviral Gag proteins which drive virus budding.

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In contrast, LPS did not enable allogeneic spleen cells to induce an anti-H-2d response. A striking anti-cancer action of IP6 has been demonstrated both in vivo and in vitro, which is based on the hypotheses that exogenously administered IP6 may be internalized, dephosphorylated to IP(1-5), and inhibit cell growth.

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The amotivational syndrome hypothesis and the Costa Rica study: relationships between methods and results. A survey of the social and psychological factors of the heroin dependence

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Combined with the clinical information, Gd-enhanced MR imaging may lead to the diagnosis and guide the therapy of meningeal carcinomatosis. The atria and ventricles were shown to differ from each other in: temporal course of contractions, relations between the strength of contractions and the interstimuli interval, resting potentiation, transitional processes after intermissions, character of response to adrenaline. A qualitative study using community based participatory methods was adopted.

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Factors associated with dysmorphic concern and psychiatric morbidity in plastic surgery outpatients. The expression of thymidylate synthase, orotic acid phosphoribosyltransferase and dihydropyrimidine dehydrogenase, which are well known to be related to drug resistance, differed among these cell lines, indicating that these cell lines acquired different resistance mechanisms. Despite the safety of electrical reversion, proper precautions are necessary to prevent complications.

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Identification of Mycobacterium leprae: use of wall-bound mycolic acids. Thus, two different H1N1 subtypes are circulating in the pig population. Blockage of transcription as a trigger for p53 accumulation by 2-acetylaminofluorene DNA-adducts.

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Antibacterial activities of the new compounds were evaluated in vitro compared with norflorxacin. An efficient method of preparing dressing materials for laser procedures. Rabbit polymorphonuclear leukocytes do not secrete endogenous pyrogens or interleukin 1 when stimulated by endotoxin, polyinosine:polycytosine, or muramyl dipeptide. This study compared patient health status, patient satisfaction, and physician practice style between family practice and internal medicine. Sustained Rhythmic Brain Activity Underlies Visual Motion Perception in Zebrafish.

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Taken together, our results directly demonstrate that a G-protein alpha-subunit can regulate the growth and pseudohyphal development of S. The compound markedly blocked CXCL12 binding to THP-1 cells (IC(50), 0.36 micro g/ml). Poorly water-soluble drug candidates often emerge from contemporary drug discovery programs, and present formulators with considerable technical challenges.

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The objective of this study was to determine if the administration of poppy seeds to horses would result in detectable concentrations of morphine in urine and blood samples, as has been shown to occur in humans. The acetates 2 and 3 were found to be unstable and were converted into the same penta-acetate 4 at room temperature. Oxygenates, mainly methyl tert-butyl ether (MTBE), are commonly added to gasoline to enhance octane index and improve combustion efficiency.

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Antiproliferative role of dopamine: loss of D2 receptors causes hormonal dysfunction and pituitary hyperplasia. Phylogenies of major groups of insects based on both morphological and molecular data have sometimes been contentious, often lacking the data to distinguish between alternative views of relationships.

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An exploratory method for estimating the changing speed of epidemic waves from historical data. Upon stimulation by bacterium-derived ligands, FLS2 and EFR interact with BAK1, a receptor-like kinase, to activate immune responses. Morphological and cytological changes in the ascites hepatoma II of buffalo rats after transplantation into F1 hybrids. Service excellence can influence overall clinical outcomes when measured by consumer awareness and patient satisfaction.

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The significance of the extracellular fluid volume for regular growth features in the infant Serum levels of proangiogenic factors IL-6, IL-8, VEGF, and bFGF may correlate with copper depletion but not with disease stability in this small cohort.

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The results from this premier mission should lead to a significant advancement in the field as a whole and to the opening of new lines of investigation for future research. Sl-IAA27 regulates strigolactone biosynthesis and mycorrhization in tomato (var. The proposed system for endoscopically-identified oesophageal features of EoE defines common nomenclature and severity scores for the assessment of EoE disease activity. (History and physical examination, x-ray tests, oesophago-gastroscopy with biopsies, 3-point-manometry, rapid pull-through manometry with pentagastrintest).

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Free dermatoplasty of the gluteal region in septic conditions following severe pelvic injury Socio-demographic data were also collected from patients and controls using an interview schedule designed for the study. How unlicensed drug vendors in rural Uganda perceive their role in the management of childhood malaria. Colchicine treatment resulted in the formation of a caplike aggregation of binding site clusters near the center of the cell, whereas cytochalasin B and 2-deoxyglucose led to the formation of patches of CABS over the entire membrane, eliminating the inward displacement of patches observed on untreated cells.

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Mercuric chloride alters the membrane potential and intracellular calcium level in mouse pancreatic islet cells. We discuss the efficacy of video-assisted thoracic surgery for multifocal bronchioloalveolar carcinoma in patients at our institution. larvae ERIC II wild-type and mutant cells with regard to (i) adhesion to primary pupal midgut cells and (ii) larval mortality as measured in exposure bioassays corroborate the assumption that the S-layer of P. The N-terminus of the Qcr7 protein of the cytochrome bc(1) complex in S.

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Catheterization of thrombosed arteries for intraarterial cancer treatment. cells were allowed to cap rhodamine-labelled Con A (TRITC-Con A). Migraine and cephalic cutaneous allodynia in pediatric patients.

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topigen pharmaceuticals careers 2013-06-12

Immunoblot revealed in spermatozoa alpha-satellite (sat) DNA-specific centromere protein B (CENP-B) and p70 (Enukashvily et al., 2000), a membrane telomere imadrax penicillin and alcohol binding protein (MTBP/TRF2) (Podgornaya et al., 2000), and Alu-binding protein p68 (Lukyanov et al., 2000). In fact, an early diagnosis is of great importance to prevent permanent neurological damage or death. On the way to nanometer-sized information of the bacterial surface by tip-enhanced Raman spectroscopy. To report a rare case of spinal dural arteriovenous fistula supplied by a lateral sacral artery and treated with endovascular therapy.

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Cultured mouse keratinocytes, which possess well-defined desmosomes, were processed for indirect immunofluorescence using the pemphigus serum samples. However, it is not always clear how different external loads influence shoulder kinematics in patients klindacin t-gel shampoo with shoulder prostheses.

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Herpes zoster ophthalmicus and acquired immune deficiency syndrome. Malawian children found to be HIV-infected through VCT had a kovar ingot vs cast mechanical properties high morbidity and mortality rate, highlighting the potential benefit of trimethoprim-sulfamethizole prophylaxis and available antiretroviral therapy.

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We dissected the interactions and their alterations by use of dute tablet covers co-immunoprecipitation and DuoLink proximity ligation assays in fibroblasts with cblG, cblE, and cblC genetic defects affecting respectively the expression of MS, methionine synthase reductase (MSR) and MMACHC and in HepG2 cells transfected with corresponding siRNAs. In addition, we showed that calcium elevated endogenous telomerase levels in a telomerase-positive ovarian cancer cell line.

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However, in our series, the predictive value of imaging was superior to that of information deduced from the previous surgical record. Histological studies of the neuroendocrine system of Gryllodes sigillatus (Walk.) in relation to wing development. We study damage spreading in the ferromagnetic Ising model on small world networks using Monte Carlo simulation with Glauber dynamics. Therefore, although Waddell signs may be predictive of treatment outcome in less intensive rehabilitation programs, they do not provide any predictive power in a comprehensive functional restoration program, herpesil 200 mg posologia pollen which has a basic goal of managing barriers to recovery in a clinically efficacious manner. Anterior rectal resections have been associated with postoperative bowel function abnormalities, a condition defined as anterior resection syndrome.

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Iodine-125, which is used for the clinical diagnosis of the thyroid gland, has a high probability of decay by K-capture followed by the emission of low-energy electrons having ranges of up to 23 micrometer. The samples were collected over a period of 2-3 years and were processed at Jordan j med virol issn online University of Science and Technology, Irbid, Jordan.

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Positive end-expiratory pressure or no positive end-expiratory pressure: is that the question to be asked? In addition, phagocytosis presents significant reduction in hemocyte monolayers treated with a specific PAF receptor antagonist, WEB 2086. The treatment of severe respiratory insufficiency in patients with chronic bronchitis and emphysema A 5-fold increase in the incidence of injuries was documented during confinement stress, and sildenafil citrate 25mg tab an interaction was found between the stressor and behavioral inhibition in the prediction of injury incidence.

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Cytotoxicity of nickel compounds was studied by stimulating the repair synthesis of DNA and counting lymphocyte micronuclei in does augmentin work for walking pneumonia workers of smelting shop of copper-nickel sulfide processing plant. Thyroid and mammary radiobiology: radiogenic damage to glandular tissue.