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We also show that the PP(523) sequence is identical to the corresponding genomic DNA sequence. Expression of human ATM cDNA in Atm-deficient mouse brain mediated by HSV-1 amplicon vector. The longer the duration of symptoms of occupational asthma (OA) before diagnosis, the poorer the outcome. Based on case material obtained through psychoanalytic psychotherapy with female patients from a psychosomatic gynecological outpatient clinic, the characteristics of the psychic structure of these patients who presented symptoms of deliberate self harm and of misusing and mistreating their children, are outlined.

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To assess whether people recognize that cancer risk increases with age and whether beliefs differ according to gender, education, smoking status, and family history of cancer. Copper ion electrochemistry in treatment of bleeding and prolapse due to hemorrhoid, experimental and clinical studies Periodontal biomechanics: finite element simulations of closing stroke and power stroke in equine cheek teeth.

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Collectively, these data suggest a rationale for clinical trials with neomycin in the treatment of gliomas. A notable consequence of CB1 cannabinoid receptor activation in vertebrates is an impairment of cognitive function related to learning and short-term memory. Hepatic mercury, selenium and renal cadmium concentrations ranged 1.5-9.8, 6.5-47.5 and 74-389 microg/g, dry wt, respectively. Further, the LBRM cells appear to be capable of oscillation between two phenotypes representing different states of lymphokine-producing cells.

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A study of possible modifications of the WHO method for testing DDT-resistance in mosquito larvae with special reference to Anopheles quadrimaculatus (Say). Damage to DNA may arise from various factors such as DNA base modifications, strand break, inter- and intrastrand crosslinks, and DNA-protein crosslinks. A case of a uniocular pterygium related to an unusual occupation. Therapeutic monitoring of tacrolimus in pediatric and adult transplanted patients.

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To evaluate cell proliferation in clinically healthy oral mucosa exposed to smoking and alcohol carcinogens over a period of 24 months using the AgNOR staining technique. Human NKT cells mediate antitumor cytotoxicity directly by recognizing target cell CD1d with bound ligand or indirectly by producing IL-2 to activate NK cells.

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Real-time polymerase chain reaction (PCR) may allow earlier and more accurate diagnosis of CDI than other currently available diagnostic tests. The enzymes involved in the reduction of nitrogenous oxides are thought to be intermediates in denitrification processes. They have been shown to lower admission rates and reduce risk of relapse. The incidence of stroke in the young Indians below the age of 40 years is higher compared to other countries, which again may be a statistical aberration or may be due to local aetiological factors. Esophagogastroduodenoscopy and gastrointestinal barium radiography are effective in screening this rare tumour.

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In this study, we examined the expression of RANKL and osteoprotegerin (OPG), a decoy receptor that prevents RANKL from binding to RANK in human periodontal ligament (PDL) cells during physiological root resorption using immunocytochemistry and reverse transcriptase polymerase chain reaction. Cyclooxygenase-1 and cyclooxygenase-2 selectivity of widely used nonsteroidal anti-inflammatory drugs. A case of disseminated tuberculosis requiring extended period for the identification of Mycobacterium tuberculosis on culture

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It is likely that the stress of having a chronic illness increases the likelihood of the development of anxiety and depressive symptoms. The authors present data of using the selective intraarterial infusion of Thienam and Vasaprostan for treatment of purulent diseases of the foot in 70 patients with diabetes mellitus. Blunt traumatic dissection of right coronary artery presenting with acute inferior wall myocardial infarction: Dilemma in management.

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We have confirmed that exposure to ultraviolet radiation lowers the denaturation temperature of type-I collagen and that the triple helical state is destroyed provided that the radiation dose exceeds a threshold level, which is defined as the incident radiation dose that raises the sample temperature above the (lower) denaturation temperature. Traumatic injuries of the ureter, bladder and urethra in pelvic fractures

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This procedure is gaining wide popularity in both Europe and the United States. Rapid and Sustained Antidepressant Action of the mGlu2/3 Receptor Antagonist MGS0039 in the Social Defeat Stress Model: Comparison with Ketamine. The proposed dual-sensitivity model was also shown to clarify some previously reported results. The degree of enhancement is also shown to indicate the extent to which a deposit has been altered, and therefore, intensity of occupation, because multiple heatings of deposits are needed to form the concentrations of iron minerals occurring in some layers. The findings are consistent with reduced female responsiveness to sympathetic activation, and substantiate the importance of including both sexes when studying neuroimmunomodulation.

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Before to these bacterial suspensions a mineral salts solution containing methyleneblue as a redox indicator had been added. Almost all squamous cell carcinomas, the vast majority of adenocarcinomas, and many rare carcinoma types are HPV related.

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Erectile dysfunction (ED) is associated with modifiable risk factors. The anorexigenic response to both dexfenfluramine and restraint stress was increased, and body weight as well as subcutaneous adipose tissue gain induced by cafeteria diet was higher in early deprived adult rats.

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Perceiving of the twins as distinct and equal legal persons forced the court to employ a balancing of incommensurate interests, implicitly accepting a utilitarian analysis within the strongly deontological confines of law and medicine. The barrelette-like pattern of the parvalbumin became discernible by immunostaining at P7 in subnuclei principalis and at P4 in subnuclei interpolaris in normal mice.

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The fatty acid composition of 35 Haemophilus influenzae strains was found to be grossly similar and characterized by relatively large amounts of 14:0, 3-OH-14:0, 16:1 and 16:0. Knowledge of pharmacology of apolipoprotein A-I has strongly increased during past years and clinical studies have started with infusions of apolipoprotein A-I phospholipid complexes.

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A large FVIII gene deletion spanning exon 2 to exon 25 was identified and we were able to obtain a 18.5 kb PCR product, which is specific for this mutation and useful for determining the carrier state in this family. This suggests that these selected endophytes produce a compound that is toxic to horses, although the toxic principle is currently unknown. Pyridine nucleotide coenzyme biosynthesis: a cellular site of oxygen toxicity. (3) The analyses of the phosphopeptides discovered were carried out in four triplicate experiments to avoid false positives getting high reproducibility in all the isolated phosphopeptides recovered from both protein kinases. strain ACN14a and complementation of Escherichia coli sod mutant.

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Embryonic viability was tested by four different transfer techniques. Both uncontrolled and controlled trials have found antidepressant drugs effective in bulimia, and they represent the pharmacotherapy of first choice. Variations in the health conditions of 6 Chicago community areas: a case for local-level data. Furthermore, histologically normal tissue adjacent to malignant colonic tissue was found to have an elevated NMR malignancy index comparable to that of malignant colon. On determination of the time of death in the first 10 hours (with reference to results with the Berlin irritation apparatus)

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A broad, systematic search of PubMed literature on antidepressant drug treatment of patients with depressive disorders with comorbid pain symptoms was carried out. The increased antioxidant activity of free HPA could be due to its more effective free radical scavenging activity and its higher concentration in the lipid phase of oil-in-water emulsions in the presence of surfactant micelles where it can act as a chain-breaking antioxidant. To identify changes in mortality and hospital use among patients admitted for ischemic stroke in Alabama.

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After giving informed consent, the patients were randomized into control and experimental groups. Participants were 14 children with a DSM-IV diagnosis of ADHD combined type and 15 matched controls. The data indicate that MT depolymerization and reorientation is correlated with reduction in growth rate, and that MT reorientation is one of the steps of growth control of graviresponding roots. Ultimately, this synaptic property might also be fundamental for the cognitive process by which we structure our experience through cause and effect relations.

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We also reviewed the medical literature (Medline 1966-2001), including the main FUO series of the previous 40 years, and laparotomy series for FUO. The MAPT p.A152T variant is a risk factor associated with tauopathies with atypical clinical and neuropathological features. The PAMAM CG model describes correctly the conformational behavior of the dendrimers, and the DMPC CG model can properly give the surface tension of the amphiphilic membrane. Recording of the retruded position of the mandible with application of varying external pressure to the lower jaw in man. The TIR domains of TLR1, 2, 4, 6, MyD88, Mal and ST2L were subjected to molecular dynamics (MD) simulations in an explicit solvent environment.

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Studies of granule formation in vitro offer additional new insights, but also important challenges for future efforts to understand how regulated secretory pathways are constructed and maintained. WBC counting, an essential part of quality monitoring of WBC-reduced blood components, is carried out logistically within 48-72 h of collection. Chronic myeloid leukemia stem cells display alterations in expression of genes involved in oxidative phosphorylation. To compare prescribing patterns in general practices before and after the introduction of fundholding in April 1993 to determine whether fundholding changed prescribing patterns among practices that joined the scheme.

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Osteomyelitis was observed in two cases, hepatosplenomegaly in one, and lymph node involvement in two. Renin heterogeneity in stroke-prone hypertensive and normotensive rats. Consistent with S-glutathionylation, streptavidin pull-down assays with biotinylated glutathione ethyl ester (BioGEE) showed incorporation of GSH to the Kir6.1 subunit in the presence of H(2)O(2).

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Apart from antibodies against mitochondrial components, primary biliary cirrhosis patients often show antibodies against nuclear components, of which anti-Sp100 and anti-gp210 are considered to be disease specific. The examinations were performed in 82 patients aged 29-70 years, treated with different types of steroids for 1-25 years. To assess mechanisms of past and potential controversies, an investigative tool is presented. In three experiments, human subjects were trained on a five-component multiple schedule with different fixed intervals of monetary reinforcement scheduled in the different components.

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The dorsal prefrontal cortex, specifically an area of the superior frontal sulcus (SFS), has been shown to exhibit greater activity for spatial than for nonspatial auditory tasks. The restriction sites of Rachiplusia ou nuclear polyhedrosis virus (RoMNPV) DNA were mapped for the endonucleases SmaI, KpnI, BamHI, SacI, XhoI, and EcoRI. Working memory involves the temporary storage and manipulation of information that is assumed to be necessary for a wide range of complex cognitive activities. Use of a pain behavior tool is one strategy to improve assessment of pain experienced by the mechanically ventilated adult patient who is unable to provide a self-report. Relations between the contractility and the frequency of the myocardium of the hamster, as compared to those of the guinea pig and the rat

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