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Within this series, compounds with therapeutically relevant HsDHODH activity are described and their binding modes characterized using X-ray crystallography, which reveals a novel conformational shift within the inhibitor binding site. The relationship of life stressors and maternal depression to pediatric asthma morbidity in a subspecialty practice. Univariate and multivariate analyses determined if concomitant PPI and clopidogrel use was associated with major adverse cardiac events (MACE). Cytochrome c oxidase is the terminal enzyme of the respiratory chain that is responsible for biological energy conversion in mitochondria and aerobic bacteria. Three potent tumor promoters of different classes, 12-O-tetradecanoylphorbol-13-acetate, dihydroteleocidin B, and aplysiatoxin, and two moderate tumor promoters, mezerein and debromoaplysiatoxin, enhanced the frequency of appearance of cadmium-resistant Chinese hamster lung cells when the cells were exposed to cytotoxic levels of CdCl2.

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Peripheral blood and bone marrow cells of patients with T-ALL, B-precursor ALL and AML were studied. The absence of certain proteins in deleted derivatives of mini-F, generated by treatment with various restriction endonucleases, allowed mapping of the proteins.

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There was no significant correlation of baseline and time-averaged follow-up HbA1c values with patient and PD technique survival. To evaluate the performance of 40-detector row computed tomography (CT) in the assessment of coronary stents in comparison with 16-detector row CT. A saccular aneurysm of the right basilar-superior cerebellar artery associated with a persistent primitive trigeminal artery (PPTA) was successfully treated by endovascular occlusion with Guglielmi detachable coils.

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A prospective study of comparison with color Doppler US, digital subtraction angiography and intraoperative data. Detection and quantification of regional wall motion abnormalities using phase analysis of equilibrium gated cardiac studies.

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The impressive wealth of collected data greatly benefits genetic counseling and stimulates efforts to develop novel avenues of targeted therapy. We show that active prolactin receptors are present in the pituitary and their expression increases in concomitance with tumor expansion. It is concluded that by using a 124Sb source for bilateral irradiation of the samples and only one BF3 counter, beryllium could be measured to an absolute sensitivity of up to 0.4 mg. In these viruses, viral resistance to NA inhibitors can be related with the presence of a defective neuraminidase RNA segment as evaluated by a plaque reduction assay, these viruses having a reduced dependence on its neuraminidase activity.

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Seven patients underwent revisional hip arthroplasty with a cementless oblong acetabular component between September 2000 and June 2002. The diagnosis is made through clinical observations made by the examiner. With a goal of improving existing mechanisms for measuring surgical quality, definitions for the occurrence of a postoperative complication need to be developed and applied consistently. Cerebral infarction following intravenous immunoglobulin therapy for Guillain-Barre syndrome. In the present work, the activities of both hexokinase and glucokinase were measured in particulated and cytosolic subcellular fractions prepared from islets first incubated for 60 min either in the absence of exogenous nutrient or in the presence of D-glucose, tested at both low (2.8 mmol/L) and high (16.7 mmol/L) concentrations.

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The present study focuses more specifically on exposure to psychological violence, and its association with turnover intentions as mediated by workplace affective commitment. In comparison, overexpression of a constitutively active PAK-1 (T423E) mutant increased MV replication in restrictive 3T3 cells. The specificity of each MAb was determined by slide agglutination tests for cross-reactivity patterns against the homologous and six other strains of Candida and a strain of Torulopsis: C. Intrinsic brainstem tumours in childhood: a report of 35 children followed for a minimum of 5 years. The combination of diabetes mellitus and pregnancy was once associated with significantly increased morbidity and mortality for mother and baby.

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Long-term safety of radiotherapy and breast cancer laterality in older survivors. By altering the TNF and IL-1 cytokines, leukocytic activation can be controlled. Subcutaneous damage of the peripheral part dorsal aponeurosis of the fingers Stenting of the ductus arteriosus and banding of the pulmonary arteries: basis for various surgical strategies in newborns with multiple left heart obstructive lesions.

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These two brand names are too similar, while the international non-proprietary names (INNs) are clearly different: lamotrigine (an antiepileptic) and terbinafine (an antifungal drug). Twelve patients had distant metastases before or at the time of repeat resection. Andrologic examinations in the antimetabolite therapy of psoriasis We therefore conclude that spectral analysis is useful for identifying functional interactions of brain regions and might provide a powerful tool to quantify changes in connectivity profiles associated with various components of an experimental task.

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This meta-analysis indicates medium-sized reduction of insula volume in schizophrenia, of greatest magnitude in the anterior subregion. A better technology of stimulation opened a wider field of patients suitable for cochlear implantation. The core-glycosylated mutant P-glycoproteins could be converted to the mature trypsin-resistant form by synthesis in the presence of drug substrate.

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Expression of alpha B-crystallin was maximum in the lens while expression of Hsp27 was absent. The optimization of intravaginal misoprostol dosing schedules in second-trimester pregnancy termination. Therapeutic advances demand accurate typing of amyloid deposits. The psychosocial experience of women with PCOS--a case control study.

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This investigation was designed as a feasibility study for this rapid version of the phase mapping method, and no in vivo studies were performed. The two-spot ladybird beetle Adalia bipunctata (Coleoptera: Coccinellidae) is host to four different intracellular maternally inherited bacteria that kill male hosts during embryogenesis: one each of the genus Rickettsia (alpha-Proteobacteria) and Spiroplasma (Mollicutes) and two distinct strains of Wolbachia (alpha-Proteobacteria). We would like to point out that such candidate genes which may code for potent growth suppressors (like p16) or even toxic gene products can be successfully investigated using the approach detailed in this manuscript. Hospital information systems are evolving towards health information systems.

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Mapping of rRNA genes and telomeric sequences in Danube salmon (Hucho hucho) chromosomes using primed in situ labeling technique (PRINS). The use of testicular sperm in assisted reproduction depends on the availability of sperm in wet preparations.

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Studies of the effect of experimental hypocupremia on the rabbit circulatory system, with special reference to the vessels of the neck and the base of the brain. Stimulation of rhesus monkey (Macaca mulatta) proacrosin activation by oviduct fluid.

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Cervical intraepithelial dysplasia (CIN 3) and history of herpes genitalis (HSV2) in women living in Attica, Greece. Our researches demonstrate the high specificity and sensitivity of IgM-ISAGA and DS-IgM-ELISA performed on whole serum.

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