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Patients were treated with bryostatin, 120 mg/m2/72 hours every 2 weeks for 3 cycles prior to re-evaluation. The affected family members present with profound prelingual sensorineural hearing impairment and use sign language for communications. BMD is affected in diabetic children, and HbA1c(whole) and diabetes duration are the most important determinants. In Down syndrome, the incidence of solid tumors including lung cancer is considerably lower than that of the general population. Three families of insect larvae (Perlidae, Baetidae, and Heptageniidae) were sampled in three pristine streams and in eight different dates.

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The protocol described herein provides a mouse model of MPM and MPD from nonhematogenous tumors, resulting in reproducible tumor location, tumor progression, animal survival, and histopathology. Nuclei of immunostained calcitonin-containing cells in both the walls of the follicles and the interfollicular compartment were not radiolabelled. Treatment of pain of diffuse metastatic cancer by stereotactic chemical hypophysectomy: long term results and observations on mechanism of action.

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Uteri rendered inactive by cross-circulation were found to be responsive to oxytocin. Sequence of the amino-terminal part of the peptidoglycan-associated lipoprotein. By 24 h after treatment, cells exposed to the tetrazepinones showed significantly greater DNA fragmentation than those previously treated with mitozolomide. It is hoped that vaccines for malaria will soon prove successful.

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In contrast, the magnocellular neurons of the preoptic area displayed strong 14-3-2 immunoreactivity. The C-terminal 122 amino acid residues of DOC-2/DAB2, containing the Grb2 binding site, is identified to be critical for the binding to myosin VI. Ten individuals with knee osteoarthritis and varus (five subjects) or valgus (five subjects) knee alignment underwent assessment of three-dimensional patellar kinematics.

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The article mentions the problem of neonatal anoxia and other perinatal hazards so much influenced by poor hygiene and ignorance, going along with other poorly understood or non existing hygienic prevention problems. Colonic temperature was significantly elevataed after exposures to power densities of 13 mW/cm2 or greater, with progressively larger increases after high intensity exposures. The main objective of the present study was to explore the impact of separation on couples where one spouse lives in a skilled nursing facility and the other spouse lives alone in the community. This interpretation relates RPRS scores to the chance for substantial improvement within 30 weeks of once weekly therapy by client-centered, rational-emotive, desensitization, aversion, or traditional methods.

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Systemic acquired resistance induced by localized virus infections in plants. Tryptophan metabolism in male Sardinian alcohol-preferring (sP) and -non-preferring (sNP) rats.

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DEH was administered in 78 applications to two groups yielding total doses of 1.1 g and 273 mg/kg body wt. A method of assessing the capability of leukocytes, particularly macrophages, to produce TNF-alpha could be useful for prognostis and for monitoring immunocompetence in patients with pancreatic cancer who have undergone chemotherapy. Therefore, beyond hemodynamic effects, specific drug-related metabolic alterations need to be considered for optimal treatment during sepsis. Cluster of Pseudomonas aeruginosa catheter-related bloodstream infections traced to contaminated multidose heparinized saline solutions in a medical ward.

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Karyometric comparison of splenic and gastric marginal zone lymphomas. We believe that the muscles in the thigh which cross both the hip and knee joints, the rectus femoris and hamstrings, play an important role in the spontaneous reduction of the joint. In summary, the benefits of somatostatin analogues given preoperatively should be considered carefully as optimisation of cardiovascular, respiratory and metabolic functions is clinically relevant for perioperative morbidity. Coll2-1 correlates well with the degenerative state of tarsocrural joints as evaluated by arthroscopy.

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Disruption strains of MgAtr1 and MgAtr2 and replacement strains of MgAtr3 and MgAtr5 displayed the same phenotype as control strains, while virulence of the MgAtr4 disruption strains was significantly reduced. To explore the mechanisms of sequence-specific ssDNA recognition, we determined the crystal structures of 10 different non-cognate ssDNAs complexed with the Oxytricha nova telomere end-binding protein (OnTEBP) and evaluated their corresponding binding affinities (PDB ID codes 1PH1-1PH9 and 1PHJ). In bronchogenic carcinoma a variety of tumor markers have been described in the last few years.

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Implementation of nursing grand rounds at a large acute hospital trust. (4) Locally aggressive osteoblastomas that are likely to recur, do not metastasize, and show characteristic and recognizable histologic features. Modern medicine has explained the relation of the cervical cancer to preterm births and to inadequate use of oral contraceptives and/or replacement, instead of supplementary, neurohormonal therapy. Time and space patterns of volatile organic compounds in a sewage treatment plant. Second, the aorta was abnormally small in calibre with hypoplastic limb vessels.

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Preseptostomy myocardial infarction in a patient with complex transposition of the great arteries. We report the case of a 38-year-old man hospitalized for a penetrating wound of the eyeball with a voluminous foreign body incarcerated in the retina.

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Formation of a compensatory polyamine by Escherichia coli polyamine-requiring mutants during growth in the absence of polyamines. Three-dimensional and ultrastructural ICAM-1 distribution in the choroid plexus, arachnoid membrane and dural sinus of inflammatory rats induced by LPS injection in the lateral ventricles. We find that the unfolding reactions for apo- and Cu(I)-forms of CopZ and Atox1, induced by the chemical denaturant, guanidine hydrochloride (GuHCl), and by thermal perturbation are reversible two-state reactions. Since C4a functions as an anaphylatoxin and significant quantities of this mediator may be generated in individuals with hereditary angioneurotic edema (HANE), the hypotheses that the kinin-like activity promoting edema in HANE patients is derived solely from component C2 and/or kininogens should be reappraised.

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Long-term post-liver transplant complications of renal impairment and diabetes mellitus: data from Singapore. It will also be necessary to implement a new paradigm of early and formal education of future health care providers into the biology of infection as well as the principles of infection control in the classroom and subsequently, with translation into their clinical training. Axial organ cells are separated into adhering and nonadhering cells by attachment ot plastic surface. The present review compares serum non-cholesterol sterols with absolute measurements of cholesterol synthesis and absorption in published papers to find out whether the serum markers are valid indicators of cholesterol metabolism in various conditions. The induction of TF by 15d-PGJ2 alone and in combination with TNF-alpha was reduced in the presence of PD 98059, suggesting the participation of the MEK/ERK pathway.

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Molecular determinants of ginkgolide binding in the glycine receptor pore. Resistant hosts were characterized by allowing significantly fewer larvae to engorge than non-resistant hosts. Hydration scanning tunneling microscopy is based on the electrical conductivity of molecularly thin water layers which adsorb to the sample surfaces in a humid atmosphere. By design participants at entry were without current major depression, substance dependence or major anxiety disorder. In this study, the 30K protein encoded by 30Kc6 was expressed in Escherichia coli.

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A Raman microprobe spectroscopy characterization of microscopic fracture mechanisms is presented for a natural hydroxyapatite material (cortical bovine femur) and two synthetic hydroxyapatite-based materials with biomimetic structures-a hydroxyapatite skeleton interpenetrated with a metallic (silver) or a polymeric (nylon-6) phase. Patients considered for arterial surgery, have been shown to have a high incidence of coexistent cardiac, vascular and other diseases, affecting operative risk and survival. The cyst wall was subsequently confirmed to be mature enough for surgical management to be initiated, and a cystojejunostomy was safely performed. The prognosis is excellent for most midfoot dislocations, as long as they are recognized and treated early.

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In the future, these new strategies may prevent or reduce caries. After regression analysis, linear equations of the relationship between changes in the mean dynamic pressure and intraocular pressure were calculated. In the present study, DNAs were extracted from 182 cases of formalin-fixed, paraffin-embedded (FFPE) colorectal cancer samples for clinical KRAS mutational analysis by direct sequencing.

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The results showed that miR-132 expression was markedly upregulated in LSCC tissues and cell lines. The first taxon belonged to the genus Tulasnella and the second taxon was distantly related to Laccaria. rhTPO stimulates platelet-leukocyte associations in whole blood through expression of platelet P-selectin. Automated clinical data can generate a readmission risk score early at hospitalization with fair discrimination.

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Contribution to the method for agglutination reaction in candidiasis Three-year SIT did not protect against development of new sensitisations in monosensitised allergic rhinitis or asthma. 31 patients impregnated their partners, 3 of whom had miscarriages. Serum samples were obtained from 40 women with pre-eclampsia and 40 normotensive, non-proteinuric pregnant women.

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The perturbation of haemostasis is the central event in the pathogenesis of all thromboses. Juvenile hyalinefibromatosis (JHF) is a rare autosomal recessive (4q21) genodermatosis characterized by a triad of cephalic fibrous outgrowths, gingival hypertrophy and flexion contractures.

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The body mass index (BMI) was not different in those who had normal compared to those who had abnormal tests. MIF- and LIF-containing fractions increased almost three-fold Fc-receptor-mediated phagocytic activity of neutrophils. Here, we show that Neuropilin-1 (NRP1), the receptor for semaphorin-3A and VEGF-A165 and a member of the immune synapse, is also a physical and functional partner of HTLV-1 envelope (Env) proteins. Iliac crest biopsy: an investigation on certain aspects of precision and accuracy. This paper deals with the capability of the ciliary epithelium to express neurolysin, involved in the inactivation of numerous neuropeptides.

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PTP-FERM was expressed predominantly in neurons in the nerve ring and the ventral nerve cord. However, the title compound differs from other type I langbeinites in that the bond-valence sums of the metal cations (in particular the Rb atoms) are practically equal to their nominal chemical valences.

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Comparison of Spinal Angles in a Typing Task on a Laptop and a Desktop Computer: A Preliminary Study. Studies on the mechanism of action of biomycin and sekazin on Rickettsia prowazekii

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The present study analyzed the copycat crimes that followed the Columbine massacre of 1999 in light of fad theory and found that a copycat crime is, essentially, a fad. The detected signals provide two servo-stabilization signals for frequency control of the carrier frequency to the resonance line center and one of the modulation frequencies to the resonance linewidth. Therefore, transmission (proximal to plate) and backscattering (distal to plate) factors were generated at several distances for each material. We sought to determine the clinical and educational impact of an integrated QI curriculum.

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The L1 cell adhesion molecule is a potential biomarker of human distal nephron injury in acute tubular necrosis. Between 1980 and 1997, six patients (seven shoulders) with glenoid dysplasia and osteoarthritis underwent shoulder arthroplasty at our institution because of moderate or severe shoulder pain. H.pylori infection, symptomatic and asymptomatic, is associated with significant pathology, and screening for the infection may be indicated for the prevention of gastroduodenal diseases. Theoretical calculation of the coiled-coil stability in water in the context of its possible use as a molecular rack.

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We suggest that perceived final positions of moving objects are based on an interplay of predictive position representations in higher motion-sensitive retinotopic areas and offset transients in primary visual cortex. The principle disadvantages include cost of the procedure, which is comparable to laparocystotomy, and the time delay required to make arrangements for use of the pulsed dye laser lithotriptor. Gelatin hydrogel was used for the controlled release of bFGF into the aneurysms.

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Potential markers that may prove more reliable and specific in their diagnostic value and that may be used for identifying patients at risk are also discussed. These results are compatible with an additional late role of Sox10 on development of neural crest derivatives, as it has been previously proposed.

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Our results suggest that vapor-phase carbenylation can be used as a complementary technology to the traditional self-assembly, permitting functionalization of various passivated substrates with stable and functional molecular coatings under mild and scalable conditions. Percutaneous cholecystostomy in acute cholecystitis--a solution for risk patient groups? Initial experience with the coaxial dual-lumen ascent balloon catheter for wide-neck aneurysm coil embolization. By contrast, higher order scattering processes render the algorithm inefficient at any finite temperature regardless of the spectral density, implying that no quantum speedup can be achieved.

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Due to their rarity and diverse symptoms they are often misdiagnosed or mistreated. OVT should be considered in any woman in the postpartum period with lower abdominal pain, fever, and leucocytosis. A simple and reproducible technique for murine platelet isolation is described. Significance of correction of metabolic acidosis on the cardiovascular dynamics.

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In 8/14 leukaemia cell samples a substantial enhancement of specific release could be repeatedly obtained by exposure of leukaemia targets to Actinomycin D for 4 h. Gefitinib-treated patients with sufficient archived tissue were included. In 2 species with the proposed primitive karyotype for the genus, telomere repeats were restricted to telomeric sites. Plant proteins containing high mobility group box DNA-binding domains modulate different nuclear processes. Host cell invasion by apicomplexan parasites requires coordinated interactions between cell surface adhesins and the parasite cytoskeleton.

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Physical activity (PA) is a preventive strategy for cardiovascular disease and for managing cardiovascular risk factors. An extended split-step time-domain model for composite coupling structures is reported. However, potential roles for HS biosynthesis in regulating the function of paracrine signaling molecules that bind to HS are incompletely understood. To enhance the sensitivity of the biosenor, glass beads were used and the thickness of the agar layer was reduced.

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The objective of this investigation was to evaluate the hypothesis that telomere DNA content (TC) in breast tumor tissues predicts breast cancer-free survival interval. Computational study on monkey VOR adaptation and smooth pursuit based on the parallel control-pathway theory.

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Furthermore a diazoacyl reagent and pepstatin, both potent inhibitors of aspartic acid-active site proteinases, were only partially inhibitory. The possible role of these loci for the control of flowering is discussed in the context of the current Arabidopsis model. Evidence for the involvement of endothelial nitric oxide synthase from smooth muscle cells in the erectile function of the human corpus cavernosum.

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Three months after operation, abdominal CT showed multiple liver metastasis. To clarify mechanisms of the antiproliferative effects of amlodipine, we evaluated effects of the expression of growth factors, the changes in phenotype, and the proliferation of VSMC from SHR. The formed architecture provided an effective matrix for annexin V with high stability and bioactivity to enhance sensitivity. Cooling gradients between normothermic blood and cooled arterial perfusate of 5 degrees, 10 degrees, 15 degrees, 20 degrees, and 0 degree C (isothermal controls) were investigated.

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Our study showed that IFRG is expressed from oocytes- through to the preimplantation embryo in rabbits. Microbial quality and direct PCR identification of lactic acid bacteria and nonpathogenic Staphylococci from artisanal low-acid sausages. Sympathectomy and immunologically induced bilateral eye reactions in the rabbit. A case of cholesterol crystal embolism following coronarography: a contraindication of the procedure? RBE-LET relationships of single-track lethal damage, sublethal damage, potentially lethal damage and DNA double-strand breaks are compared.

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We conclude that the biological outcome of aberrant LEF1 activation in colon cancer is directed by differential promoter activation and repression. No overreaction then occurred and many acid-labile functional groups could remain intact. On average, it took about 1 min less when using the push-button response than when using hand-raise or verbal response methods.

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Observations on Microfilaria fijiensis Yeh, Symes and Mataika, 1958 from fruit bats (Pteropus hawaiiensis in Fiji. To determine whether receipt of anthrax vaccination by reproductive-aged women has an effect on pregnancy rates. The aim of this study was to investigate whether the binding of SLE autoantibodies to apoptotic cells influences the phagocytosis of these cells by macrophages. Of 65 subjects examined, normal patellar tendon sonographic anatomy was defined in 32. Certain restrictions are necessary regarding carriage of sick passengers on commercial aircraft whether jet-propelled or of propeller type.

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Only one of the three studied populations showed a negative trend which was probably caused by the introduction of fish. Agreement of pesticide biomarkers between morning void and 24-h urine samples from farmers and their children. Logistic regression revealed that among the risk factors found to increase GI, the following proved significant (in order of importance): plaque index, subgingival encroachment of the cervical margins of bands, probing depth, and length of orthodontic treatment. In Japan, tea (Camellia sinenis (L.) Kuntze) seedlings are propagated by cutting.

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The SBA-15-SO3H gives significant selectivity for glycopeptides even at a low molar ratio of glycopeptides to nonglycopeptides with an enrichment time of 15min. The expression of 44 genes identified in Cohort 1 was assessed at weeks 0 and 4, and was then correlated with biomarkers, as well as with clinical, endoscopic, and histologic scores. Data were analyzed to assess if selected socio-demographic variables were associated with having smoked cigarettes. Excision of the base of the middle metacarpal allowed easier approximation of the index and ring rays without the tendency of these fingers to either scissor on finger flexion or to remain slightly apart.