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Fulvicin (Griseofulvin)

Fulvicin has been available since 1958 to treat ringworm (tinea). It is not effective against yeasts such as candida or malassezia. Fulvicin has been withdrawn from the market in New Zealand (2002) and other countries, as it has been superceded by more effective and safer antifungal drugs. Fulvicin comes from the mould, Penicillium griseofulvum. It stops fungal cells dividing (i.e. it is fungistatic) but does not kill them outright. This means treatment needs to be continued for several weeks or months. For many fungal infections, especially of the nail (tinea unguium), newer drugs work better than Fulvicin. Fulvicin may still be preferable for tinea capitis, especially when due to Microsporum canis infection, and is generally well tolerated in children. Fulvicin tablets are not very well absorbed from the gut. They should be taken after a meal or drink of milk as fat increases the absorption. The medication is carried into the skin by sweat and within a couple of weeks is concentrated in the outer skin layers.

Other names for this medication:
Griseofulvin, Grifulvin, Fulcin, Fulvicin, Fulviderm, Fungistop, Grifulin, Grisetin, Griseofulvina,

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Synucleins in glaucoma: implication of gamma-synuclein in glaucomatous alterations in the optic nerve. In the present study, we examined whether tDCS can reach and selectively modulate the excitability of the frontal eye field (FEF). The treatment of superficial fungus infections in man with orally administered griseofulvin. Penile plethysmography during sleep provides useful information.

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