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A description and commentary is given for an unnoticed sheet of formulae and arguments in the hand of Robert Robinson concerning the structure of penicillin. Individual and synergistic effects of sniffing frequency and flow rate on olfactory bulb activity. In the study we evaluated the effectiveness of intraarticular injected hyaluronic acid (Hyalart) with regard to the changes in the parameters maximal isokinetic muscle strength, total work, pain at rest, and pain under toad. Iontophoretic nefopam (1 mM, 50-80 nA, positive current) in normal rats did not change the spontaneous neuronal activity, but reduced the mean response to noxious stimuli and the concurrent iontophoretic NMDA evoked activity.

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Percutaneous graduated thermocoagulation of the Gasserian ganglion in trigeminal neuralgia. Though antibiotics are the mainstay of treatment, surgical debridement with the use of instrumentation may be indicated in selected patients. First, in the early period of the training, ego functions were systematically undermined and regression was promoted. This report describes the different acquisition protocols adapted for children and illustrates the present role of volumic CT scanner in congenital heart disease by clinical examples of everyday clinical practice.

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Background Due to increasing healthcare costs, discussions regarding increased hospital costs when operating on high-risk patients is rising. Homogeneous substrate-labeled fluorescent immunoassay for disopyramide in human serum: semi- and fully automated procedures. Furthermore, we show that activation of platelets results in the release of soluble glycosyltransferase activities and that platelets contain sufficient levels of sugar nucleotides for detection of glycosylation of exogenously added substrates.

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V-Y fasciocutaneous flap closure technique is a safe and efficacious alternative to primary closure of the perineal wound following abdominoperineal resection. In two uremic patients with scleroderma, the effects were studied of the removal, by pheresis, of antinuclear antibodies, immune complexes, and immunoglobulin factors perpetuating the inflammatory response. Involvement of endogenous opioids and ATP-sensitive potassium channels in the mediation of carbachol-induced antinociception at the spinal level: a behavioral study in rats. Letter: In-vitro confirmation of genetic compound of the Hurler and Scheie syndromes.

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Maternal tachycardia should be considered as an index of patient responsiveness to the beta-mimetic treatment. Prolonged intermittent positive pressure ventilation by nasal prongs in intractable apnea of prematurity. Finally, the evidence is reviewed that indicates familial thrombosis as an oligogenetic disorder and on the basis of these data strategies are discussed for the identification of new genetic risk factors for thrombosis via a genetic approach.

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In order to reduce cost and duration of diagnosis, every centre should determine its own most frequent etiologic factors. Evaluating the thermostability of commercial fast real-time PCR master mixes. Recent investigations have shown that glibenclamide inhibits the opening of vascular ATP-sensitive potassium channels during ischemia. We report a case of occupational contact dermatitis that was transferred with job duties. The role of these two agents in the causation of the acute renal failure is discussed.

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We further show that reduced expression of the type II TGF-beta receptor correlates with loss of luminal differentiation in a clinical breast cancer cohort, suggesting that this mechanism may be clinically relevant. Selection for the length of the spermatozoan midpiece in the mouse. Remarkably, TLR4 coimmunoprecipitated with FAK, and small interfering RNA-mediated FAK inhibition restored enterocyte migration after TLR4 activation, demonstrating that the FAK-TLR4 association regulates intestinal healing. IL-17 may be a potential therapeutic target for inflammatory diseases in humans, such as rheumatoid arthritis.

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In addition to hydrolysis, acyl migration fro the 21-hydroxyl group was found to be an important reaction. Paclitaxel (Taxol (TM)), is an anti-cancer drug in short supply. CFS was diagnosed according to IIIP-revised CDC-criteria as defined by the CFS Expert Advisory Group to the German Federal Ministry of Health in 1994. The second method uses an injected fluorinated agent which has a T (1) that is sensitive to tissue oxygen levels. The principal clinical features in three 4-week-old Holstein-Friesian heifers intravenously inoculated were fever, listlessness, anorexia, weakness, and diarrhea.

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Simple laboratory analysis will show whether the reaction is due to an underlying immunopathological condition that may be triggered by any of several drugs. For this purpose, both tumor bearers and diabetic animals have been treated with dehydroepiandrosterone (DHEA), a multifunctional steroid endowed with multitargeted antioxidant properties. Results of a randomized trial in children with Acute Myeloid Leukaemia: medical research council AML12 trial. Recent developments in laser technology of interest to the practitioner.

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external control, time perspective and delay of gratification of high and low ego strength groups. Results indicate that patients with primary mood disorders have a circumscribed numerical neuronal deficiency in the dorsal raphe. The aim of this study was to compare the aesthetic results of post traumatic rhinoplasty among Europeans with populations of healthy Caucasians described in earlier reports, and to collate correct parameters of nasal shape in healthy representatives of both sexes and various races for improvement in aesthetic results of surgery.

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Four complete responders have relapsed, 1 in the central nervous system at 6 mo. We propose a model for rat tissue uptake consistent with the presence of two different TC-B(12) receptors and renal uptake following filtration of TC-B(12) in the glomeruli. Thiophene-2-carbaldehyde N-(2,4-dinitrophenyl)-N-methylhydrazone. Retrospective, longitudinal analysis of sensory, motor and functional outcomes from individuals with thoracic (T2-T12) sensorimotor complete spinal cord injury (SCI).

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The study shows that US veterans receiving health care at VAMC are a high risk group for both AIDS and TB, and increased preventive measures are recommended. Bipolar disorder and severe premenstrual syndrome (PMS) have many symptoms in common, but it is important to establish the correct diagnosis between a severe psychiatric disorder and an endocrine disorder appropriately treatable with hormones. Cx26 and the closely related Cx30 showed differential expression in epidermal, adnexal, and corneal epithelia but were not significantly altered in lesional skin. The aim of this study was to demonstrate that complete and reversible sinusoidal high frequency alternating current (HFAC) conduction block of the pudendal nerves (PN) can eliminate external urethral sphincter activation and produce low residual bladder voiding.

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The radicular cyst is characterized by the presence of a cavity, partially or wholly lined by epithelium. Effects of High-Seas Driftnet Fisheries on the Northern Right Whale Dolphin Lissodelphis Borealis. No mutations were identified in the candidate genes LRPB2BP, CYP4V2, and UFSP2. Considerable variability was exhibited at increasing aquifer depth, more so with 2,4-D than with MCPA.

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This will result in cost reduction and improve quality assessment of lung function devices. Univariate and multivariate analyses were performed to evaluate the risk factors associated with the development of acute hepatic failure after TACE. An autopsy case of a late form of familial amaurotic idiocy in comparison to the clinical and pathological findings on the two siblings with the same disease In rats with renal hypertension the activation of noradrenergic neurons in the hypothalamus was due to exhaustion of NA stores with normal amount of DA, but still the adrenergic neurons were activated. Simple apparatus for support-free preparative filter electrophoresis

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Botulinum toxin type A injection in the treatment of lichen simplex: an open pilot study. Wireless technology: communications and challenges in healthcare. Hyperpolarization of muscle by insulin in a glucose-free environment. This resource consumption is focused on a relatively small number of patients. Co-expression of MT1-MMP with syndecan-1 in HEK293T cells promoted syndecan-1 shedding, and concentration of cell-associated syndecan-1 was reduced.

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SFTG international collaborative study on in vitro micronucleus test V. Cognitive impairment is present in poor-outcome patients with affective disorders as well as schizophrenia, suggesting that cognitive impairments predict poor outcome across psychiatric disorders and not just in schizophrenia. Neuronal nitric oxide synthase (bNOS) messenger RNA and protein expression in developing rat brainstem nuclei.

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Foreign-body-induced carcinogenesis is a traditional, maybe old, way of understanding cancer development. Treatments for brain edema are important and one of the major options is corticosteroids. In both cases, the leak completely resolved with use of tube feedings with medium chain triglycerides. Repair was done using polytetrafluoroethylene chordal reimplantation for both leaflets.

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The results showed that amygdala kindling was facilitated in alcohol-withdrawal kindled animals which showed spontaneous withdrawal seizure activity, compared with animals exposed to multiple episodes of alcohol withdrawal which did not develop withdrawal seizures or with animals exposed to a single episode of alcohol intoxication. We examined similarities and differences in the neural response to SSRIs and placebo in patients with social anxiety disorder (SAD). In Alzheimer disease (AD), mounting evidence points to a greater role for synaptic loss than neuronal loss.

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Sixty-six men with AGA received finasteride, 1 mg/d, or placebo in a 48-week study, and 49 men continued in a 48-week extension. The structures of Ac-I1L/H9W/T13G and Ac-compstatin were studied by nuclear magnetic resonance, compared with the structure of compstatin, and found to be very similar.

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Variation of alpha 1, alpha 2 and beta fractions is inconstant and is not of great diagnostic or prognostic value. These results suggest that an increase of H2O2 and/or peroxide by compound 4 is the initial apoptotic event. Structural and serological studies of the O-antigen of Proteus mirabilis O-9.

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One thousand women were interviewed about their reproductive behavior, 24 to 72 hours after pregnancy resolution. However, the dominant inhibition of sporulation by Nos1 was gradually lost with increasing time between induction by light and time of fusion, suggesting that Nos1 can be bypassed by the time-dependent formation of a downstream signal-transduction intermediate.

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Presentation of a patient recently operated for hydatid cyst of the lung Improvement in the suspension-culture production of recombinant adeno-associated virus-LacZ in HEK-293 cells using polyethyleneimine-DNA complexes in combination with hypothermic treatment.

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RRE is a complex 351-nt RNA that is highly structured and located within the viral env gene. Other than lysoPAF AT activity, Lpt1 catalyzed acyltransferase activity with a wide variety of lysophospholipids as acceptors, including lysophosphatidic acid, lysophosphatidylcholine, lysophosphatidylethanolamine, lysophosphatidylglycerol, lysophosphatidylinositol, and lysophosphatidylserine. The HEWS integrates data from communications, remote-sensing and positioning satellites.

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Repopulation in murine breast tumors during and after sequential treatments with cyclophosphamide and 5-fluorouracil. An important emerging theme is determining the age-dependent alterations that occur at the organ level and how this functional senescence is regulated by different tissues.

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Negative effect of immediate hyperbaric oxygen therapy in acute acoustic trauma. New findings supporting the existence of these antibodies in various experimental systems were presented. We will present results from over 3 years of studies that used laboratory- and breadboard-scale (8 and 120 L working volumes, respectively) aerobic, fed-batch, continuous stirred tank reactors (CSTR) for recovery of carbon and minerals from breadboard grown wheat and white potato residues.

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Two pathways for induction of apoptosis by ultraviolet radiation in cultured human keratinocytes. Compensatory strategies for acquired disorders of memory and planning: differential effects of a paging system for patients with brain injury of traumatic versus cerebrovascular aetiology. The history of the surgery of esophageal atresia (based on data from the Saint-Petersburg Center for Neonatal Surgery)

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To test the hypothesis that older men who consumed a vegetarian (lacto-ovo) diet would develop a lower iron status compared with older men who consumed a beef-containing diet during a period of resistive training (RT). In patients with ischemic heart diseases and aortic dissection, an accurate history and a chest roentgenogram can serve as helpful guides to their diagnosis, and ultrasound, computed tomography, and electrocardiography can establish the diagnosis. This article describes these consultations, including information on the requesting caregivers, the patients, the questions asked and the recommendations given in the first 26 months.

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Theory of slow light enhanced four-wave mixing in photonic crystal waveguides. A more promising strategy would be to adopt forms of reflexive regulation which mobilize the self-regulatory capacities of medical professionals themselves. In our study systematic management of hypertensive patients aged 50 to 65 in general practice was associated with a statistically significant, and clinically relevant decrease in cardiovascular morbidity and blood pressure.

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HdEEG allowed to investigate sleep rhythms in terms of their characteristic behavior (e.g., the traveling of slow waves) and in terms of their relationship to cortical functioning (e.g., consciousness and cognitive abilities). Angiotensin (ANG) II interacts with insulin-signaling pathways to regulate insulin sensitivity.

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In recent years, advancement in technologies has led to the identification of genes associated with several eye disorders. This prospective study included 120 patients with LV dysfunction who underwent 99mTechnetium-Sestamibi myocardial perfusion SPECT-CT and 18FFDG cardiac PET-CT. The excitatory actions of EtOH may be perceived as positive by some individuals, which could contribute to the development of alcoholism. Eleven months after trauma, the treated teeth exhibited good healing and normal function. Furthermore, serological characterization of the interferon species produced locally may predict which particular interferon species could be of the greatest therapeutic benefit in specific disease states or individual patients.

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Histological features showed marked cholestasis with multiple bile plugs in dilated canaliculi. A total of 57 patients, on whom surgical esophageal resection had been performed between 1993 and 2000, were enrolled in this study. Moreover, inhibition of Hh activity by Hh pathway-specific inhibitors leads to cell cycle arrest and apoptosis in CEM (human acute lymphoblastic leukemia, T lineage) cells, and the GC-sensitive clone is more sensitive to Hh inhibition. In posterior-segment penetrating injuries, the role of cellular and extracellular structures for the development of fraction retinal detachment is a matter of controversy. Prion-related encephalopathies are characterized by astrogliosis and nerve cell degeneration and loss.

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Induction of the lymphatic-like phenotype is partially inhibited by co-culture of HUVECs with perivascular cells. Comparative in vitro activity of three fluoroquinolones against clinical isolates by E test.

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The crystalloids were yellow to green, measured 30-50 microns in diameter and were radially arranged. Increased cellular level of ceramide by the co-administration induced the association between Akt and Protein Phosphatase 1 (PP1) to dephosphorylate Akt, and to introduce a constitutively active Akt (CA-Akt) restored Akt activation and diminished cell growth inhibition. Furthermore, substantial numbers of rat mphi can be isolated from various sites (e.g. Humans experience a similar loss under certain conditions on Earth. On the roles of calcium ion during potassium induced contracture in the smooth muscle cells of the rabbit main pulmonary artery.

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Adipose-derived mesenchymal stromal cells for chronic myocardial ischemia (MyStromalCell Trial): study design. The results of our investigation indicated that continuous EEG monitoring of mannitol treatment can reflect the brain edema, raised ICP in stroke patients, and provide assessment the drugs effects of antiedema and intracranial pressure lowering in vivo. Role of diet components in the genesis of cancer of the large intestine We evaluated associations between 5-yr graft survival and total, locus-specific, and haplotype match levels.

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Based on the high prevalence of chronic respiratory disease symptoms, this study emphasizes an emerging occupational concern in agriculture to the estimated 500,000 persons working in swine confinement operations and the estimated 500,000 additional persons who work in poultry, veal, beef, or dairy confinement operations. However, the observation that patients tend to increase their discarding intervals implies that practitioners could do better in educating their patients as to discarding intervals and in prescribing products that best match patient needs for both convenience and cost.

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The His5-Leu6, His10-Leu11, and Gly23-Phe24 bonds were also cleaved but at considerably slower rates. Slow infusion of vincristine in the treatment of idiopathic thrombocytopenic purpura. Different neuroregulators may affect different stimuli that impact eating behavior. Screening can be expensive in time and money, and ineffective, and is therefore unpopular with general practitioners (GPs). These results suggest that when dopamine is released in the dentate gyrus with concurrent high-frequency activity there is an increased probability that synapses will be strengthened and reward-associated spatial memories will be formed.

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These data suggest that IGF-1 induced the activation of Akt and CREB using distinct pathways in PC12 cells. School-based drug prevention programs have been criticized on methodologic grounds because the unit of analysis is often not the unit of randomization, thus increasing the likelihood of Type I errors. Therefore, combining current steering and current focusing may provide more effective spectral cues than are currently available. Of these patients 62 (59 per cent) had documented infections and 41 (66 per cent) were infected with doxycycline-sensitive organisms: 24 were randomized to a 4-day course and 17 to a 10-day course of antibiotic.

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Of particular interest was the finding that the relationship between pain intensity and fearful thinking about pain was less strong for those high in acceptance. It was associated with an overlying, irregular, verrucoid epidermal plaque. Meanwhile, the zeta potential of TCP sintered at 900 degrees C showed a highly negative charge when compared with the other groups.