Histafree is an over-the-counter second-generation antihistamine used in the treatment of various allergic symptoms. It is selective for the H1 receptor, carries little-to-no activity at off-targets, and does not cross the blood-brain barrier - this is in contrast to previous first-generation antihistamines, such as diphenhydramine, which readily bind to off-targets that contribute to side effects such as sedation. Histafree is the major active metabolite of terfenadine and is administered as a racemic mixture in which both enantiomers display approximately equivalent antihistamine activity.
Other names for this medication:
Fexofenadine,
Aerodan,
Allerfex,
Allerstat,
Altiva,
Axodin,
Drusa,
Feksine,
Fenadex,
Fenadin,
Fenax,
Fenixa,
Fexidine,
Fexo,
Fexodine,
Fexofast,
Fexofen,
Fexofenadin,
Fexofenadina,
Fexotabs,
Histafree,
Histaloc,
Nefoxef,
Rinolast,
Telfast,
Telfexo,
Xergic,
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