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Antinociceptive potency of aminoglycoside antibiotics and magnesium chloride: a comparative study on models of phasic and incisional pain in rats. A phase II trial of neoadjuvant cisplatin-fluorouracil followed by postoperative intraperitoneal floxuridine-leucovorin in patients with locally advanced gastric cancer.

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A feature of this amplitude is its generality and simplicity making it useful for widespread applications in resonance theory. As a first step, organophosphate insecticide use has been reduced as they have high acute toxicity and risk of long-term neurological consequences. In this article, the distribution of the purinergic receptors in the gastrointestinal tract and their physiological and pathophysiological role in intestinal inflammation will be reviewed.

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Transposons have several advantages over T-DNA including the ability to produce multiple independent insertion lines from individual starter lines, as well as producing revertants by remobilization. We concluded that the central regulatory unit composed of AdpA and BldA plays important roles in the initiation of morphological differentiation and secondary metabolism triggered by A-factor. In immunocytochemical experiments on human kidney tissue with an antiserum directed against the prosegment of renin, only juvenile granules were clearly labeled. What are presumed to be the displaced cell bodies of both rods and horizontal cells are often noted within the outer plexiform layer of this species. Sensory hair cells in the inner ears of nonmammalian vertebrates can regenerate after injury.

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Raman spectroscopy is a non-destructive, rapid analysis technique that requires only small sample volumes and has recently been used to evaluate the mineral content, mineral crystallinity, acid phosphate and carbonate contents, and collagen maturity in human and animal bones. 241 hospitalised but medically stable elderly patients who fulfilled criteria for early discharge to hospital at home scheme and who consented to participate. Oxidative stress has been implicated in sarcopenia and the loss of muscle strength with aging, but the relationship between oxidative stress and decrease in muscle strength and physical performance has not been well characterized. A case is presented of a baby in whom the abdominal catheter of a ventriculoperitoneal shunt entered the thoracic cavity.

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The developed program consists of 13 self-paced print modules with web-based components and is primarily asynchronous with scheduled milestones. High activities of the enzymes orotate phosphoribosyltransferase and orotidylate decarboxylase, that convert orotic acid to uridine monophosphate, have been demonstrated in crude supernatants obtained from lysed Plasmodium berghei.

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The role of anti-idiotypic subclass-specific antibodies was analysed in the regulation of the immune response to BCG in the guinea-pig. Serum amyloid A (SAA)--pathogenicity and implication of appearance in plasma Presynaptic nerve terminals of inhibitory synapses in the dorsal horn of the spinal cord and brain stem can release both GABA and glycine, leading to coactivation of postsynaptic GABAA and glycine receptors.

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These results indicate that the biological activity of the toxin involves a novel enzymatic activity of component I, which catalyzes the preferential ADP-ribosylation of nonmuscle actin of the target cells. In the porcine overstretch injury model of restenosis, endovascular beta-radiation reduces neointima formation. Aspiration of oral secretions and their bacteria is increasingly being recognized as an important factor in pneumonia. Two of the promoters that might play a role in head and neck cancer gene therapy are the hyperthermia-inducible human heat shock protein-70 (hsp70) promotor, as well as the radiation-inducible promoter of the early growth response-1 gene (egr-1).

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To increase the proportion of ischemic stroke patients treated with thrombolytic therapy, the establishment of primary stroke centers in community hospitals has been advocated. Production of the Alternaria mycotoxins alternariol (AOH), alternariol monomethylether (AME) and tenuazonic acid (TA) by Alternaria alternata DSM 12633 was influenced by pH and carbon to nitrogen (C:N) ratio of the growth medium both in shaking flasks and bioreactor cultivation. Complementary roles of herbal medicine and exercise were reported from five studies. Electrophysiological characteristics of interoceptive reflex arch. Northern blot and pulse-chase analyses revealed that this reduction was not regulated at a transcriptional level but by accelerated p27 degradation via a proteasome-dependent pathway.

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Shigella flexneri 2a is known to express the H-NS nucleoid-structuring protein and the paralogous protein StpA. Study of the comparative sensitivity, in research on the Koch bacillus, of cultures after treating samples with teepol and of inoculation of guinea pigs The LH-RH levels in the CSF of post-menopausal women were not higher their those in the remaining 3 groups, although their plasma levels of LH-RH were significantly (p less than 0.001) elevated.

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The term veno-occlusive disease of the liver refers to a form of toxic liver injury characterized clinically by the development of hepatomegaly, ascites, and jaundice, and histologically by diffuse damage in the centrilobular zone of the liver. Human bone and kidney sections, benign and lymphomatous pleural effusions were processed for silver staining to identify AgNOR. Impact of total lymph node count and lymph node ratio on staging and survival after pancreatectomy for pancreatic adenocarcinoma: a large, population-based analysis. In cultured cells that normally do not respond to light, heterologous expression of mammalian melanopsin confers light sensitivity that can be restored by prior stimulation with appropriate wavelengths. Data were pooled from seven pegfilgrastim registrational clinical trials: four open-label phase I or II studies and three randomized phase II or III studies.

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Modeling and simulation of hepatic drug disposition using a physiologically based, multi-agent in silico liver. (1) To validate the mixture model in a single operator dataset and (2) to compare the detection rates for fetal chromosomal defects obtained from the mixture model with those obtained from either the delta nuchal translucency (NT) or log multiple of the median (MoM) approach. C6 cells were treated with a single fraction of ?-60Co radiation at various doses (0, 4, 16, and 64 Gy). The msp1beta sequences were highly conserved throughout infection. Carrier detection in families affected by Duchenne/Becker muscular dystrophy

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Estrogen and inflammation: hormone generous action spreads to the brain. The aim of this study was to evaluate the enhancement characteristics of orbital lymphoma and SCIPT with two-phase helical computed tomography (CT) and delayed coronal CT and to determine whether attenuation measurements on CT can be used to differentiate between the 2 diseases. Immunohistochemical characterization of calcitonin gene-related peptide in the trigeminal system of the familial hemiplegic migraine 1 knock-in mouse. An interesting consequence of single occupancy is that the flux has a maximum as a function of the channel-solute interaction. We established methodology for the measurement of bradykinin and kallidin peptides and their metabolites in order to study the function of the plasma and tissue KKS in humans.

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We specifically studied the differences in male-female ratio, age, TNM-stage, site distribution, and alcohol and tobacco use. The goal of this work is to advance 3D puzzle-solving methods towards use as a preoperative tool for reconstructing these complex fractures. Injury incidence, prevalence, and severity were calculated for each grade level and player position. One tape, shown to half of the parents, had a brief explanation and rationale of the specific behavior management technique before its demonstration (Group A).

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Frequency versus relaxation oscillations in a semiconductor laser with coherent filtered optical feedback. To investigate whether normal-appearing brain tissue (NABT) on conventional MRI has occult damage in patients with relapsing-remitting multiple sclerosis (RRMS) by using diffusion tensor imaging (DTI) histogram analysis, and to determine the correlations between DTI histogram-derived measures of the NABT and expanded disability status scale (EDSS) scores, disease durations, T2WI lesion volumes and brain tissue volumes in RRMS patients.

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The advantage of this approach is correct orientation and introduction of the endoscope to the periventricular lesion because the usual landmarks can be identified in the normal contralateral lateral ventricle. Medical and communicative training must be an important part of the continuous improvement strategy within the out-of-hour services. Eighty-five consecutive diabetic patients who underwent cataract surgery were categorized according to their type of diabetes, duration and treatment, operative technique, pre-operative visual acuity (VA) and degree of retinopathy. Anterior semifundoplication in the treatment of gastroesophageal reflux disease: long-term results following conventional surgery Osteochondrosis and osteochondral fragments in Standardbred trotters: prevalence and relationships.

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Classification of every individual case of amyloid disease is necessary in order to recognize its origin and its possible pathogenesis for therapeutic consideration. Two hundred twenty-six women with an isolated pelvic mass had a serum CEA determination preoperatively. Glutamate inhibits chondral mineralization through apoptotic cell death mediated by retrograde operation of the cystine/glutamate antiporter.

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Although stressing polymers have been widely and successfully used to determine the osmotic properties of solutes in aqueous media, the osmotic stress method presents some limitations. Massive liver growth in mice induced by systemic interleukin 6 administration. A profile of prospective patients at the University of Maryland, School of Dentistry. In the mammalian parietal cells an intracellular system of canaliculi is also observed, which is much more complex in the rat than in the cat or dog.

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Pigmentation may result from melanocyte proliferation, melanogenesis, migration or increases in dendricity. The authors report the experience of using long coils of 2 m length in the management of large aneurysms. Our group developed a method that allowed the simultaneous evaluation of blood flow in human cerebral aneurysms using digital subtraction angiography (DSA) with no special devices. T x B hybrid clones capable of inhibiting the development of leukosis in vivo To test this, we subjected multiple Arabidopsis thaliana accessions to chemical genetic screens and discovered 12 accession-selective hit molecules.

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In addition, Oxyrase treatment increased the basal activity of mitogen-activated protein kinase (ERK1/2) but suppressed its activation induced by radiation. The first 1D twofold interpenetrating metal-organic network generated by 1D triple helical chains with nanosized cages. GC-rich fragments of human DNA may be used for preconditioning of therapeutic MSCs aiming at an increase in their survival in the ailing body.

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Along this line, a cDNA expression library was established from an embryonic stem cell-based in vitro model of cardiogenesis, and screened for clones that would induce an increase in cell size in cultured cardiomyocytes. Identifying and modulating disulfide formation in the biopharmaceutical production of a recombinant protein vaccine candidate. Cellular SR-BI and ABCA1-mediated cholesterol efflux are gender-specific in healthy subjects. Transport of plutonium in surface and sub-surface waters from the Arctic shelf to the North Pole via the Lomonosov Ridge.

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The effect of turning and clinostating, exposures on the early embryogenesis of the teleost B. Paraoxonase-1 (PON1) is an enzyme with numerous functions and receives an increasing interest in clinical and epidemiological studies.

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On the other hand, sympathetic nerves originating from the cervical ganglia reached the grafted pineal along the perivascular spaces of blood vessels, as is the case in situ. It is discusses their possible association with Klippel-Feil syndrome.

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A group of 70 children with NF1 was compared to age-matched controls. Work in progress related to translation and cultural biases in terminology is briefly described.

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From this perspective, slow diffusion occurs just because these optimal paths become particularly long and convoluted. Thus, at this time, more studies are needed to definitively conclude that vitamin D can offer preventive and therapeutic benefits across a wide range of physiological states and chronic nonskeletal disorders. Immunoelectrophoretic studies on the origin of gamma globulin in the newborn

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The rate at which peripheral blood glucose levels changed was examined in relation to cognitive performance. The continuum model of bulimia nervosa suggests that dieting plays a major role in the etiology and maintenance of bulimia. Fine detail and heavily penetrated radiographs produce needed bony, especially trabecular, and detail and allow the film reviewers to exlude simulating lesions. Emergency heart valve replacement after acute cerebral embolism during florid endocarditis

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Therefore, it was decided to investigate the effect of nizatidine and omeprazole on the oxidative respiratory chain, as it is known that metronidazole is able to inhibit the activity of fumarate reductase of H. Recent studies have also shown that activation of TLR3 and RLR signaling by polyi:c can directly trigger apoptosis in some cancer cells. Insulin binding to IgG measured by an immunoelectrophoretic method, was followed at 3-month intervals for 1 year, and did not change after the transfer. Research on elementary postural reflexes (fixation and opposition reflexes

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Vitreous fluorescein accumulation determined by in vivo fluorophotometry and by vitreous extraction in normal and diabetic rats. ATP-binding cassette transporters from several rhizobia and Salmonella enterica serovar Typhimurium, but not secondarily coupled systems, were inhibited by high concentrations (100 to 500 mM) of various osmolytes, an effect reversed by the removal of the osmolyte. More recently, it has become clear that colon cancer can arise via various histological pathways, and by various genetic pathways. With the ultimate purpose of testing the existence of possible differences in the effectiveness of the topoisomerase II catalytic inhibitor ICRF-193 (a bisdioxopiperazine) and the enzyme suppressor bufalin (a bufadienolide from toad venom) we have carried out a series of experiments aimed at inducing cytotoxicity as well as DNA and chromosome damage in transformed CHO cells.

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Selective targeting of zebrafish olfactory receptor neurons by the endogenous OMP promoter. Efficacy of native carvedilol in patients with essential hypertension

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It is characterized by a high level of serum IgG4 and dense infiltration of IgG4-positive plasma cells into multiple organs, with the kidney being one representative target. Zooplankton mortality and the dynamical behaviour of plankton population models. The Anatomical Therapeutic Chemical classification and the defined daily dose (DDD)/1,000 methodology are used to calculate antibiotic consumption.

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The four papers presented in this journal test three key intergenerational research questions regarding intergenerational continuities for externalizing behaviors, using different 3-generational samples. Infusions of plasma-derived MBL into MBL-deficient individuals was found to be safe in preliminary trials, but we considered that sufficient production and product safety could only be achieved through synthesis of recombinant MBL.