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Thus, PLHKEM1, DEF8, FAM98A, and NDEL1 constitute a molecular complex that regulates lysosome positioning and secretion through RAB7. mechanical circulatory support in severe inotrope-dependent acute heart failure. A comparative study of eight distinct beta-lactamases synthesized by gram-negative bacteria. The effect of radiation on the growth of vertebrae in the tails of rats.

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However, IL-2, when added in high concentrations (200-1,000 U/ml) during the early (IL-1-dependent) phase of the B cell response inhibited antibody production.(ABSTRACT TRUNCATED AT 250 WORDS) Human monocytes are insulin target cells and capable of fatty acid metabolism to some extent. Because information in a digital format can be stored, processed, and transmitted easily and efficiently by computers, traditional imaging receptors, such as conventional radiographic film, is slowly being replaced. Urinary diarrhea detected by Tc-99m DTPA scintigraphy in a 3-year-old girl. An alternative treatment is the use of peptide immunomodulatory therapy to enhance cytokine production, immune cell function and resistance to opportunistic infections.

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All the traits studied were significantly influenced by environmental conditions. Construction of a mutant, in which the torD gene is interrupted, showed that the absence of TorD protein leads to a two times decrease of the final amount of TorA enzyme.

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Our results indicate the possibility of preventing West Syndrome with good quality obstetric and neonatal care, as well as the early prenatal diagnosis of brain malformations. The relation of fetal nutrition to TC appears to be weak and is probably of limited public health importance when compared with the effects of childhood obesity. In the adult human population, the most frequent cardiac pathologies emanate from a decompensated lost of myocardial function.

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Reconstruction of the lumbar-sacrum joint by the USS after resection of sacrum tumor is a practical operation clinically. The brain orexin system and almorexant in fear-conditioned startle reactions in the rat. Chromatin is considered to be a principal carrier of epigenetic information due to the ability of alternative chromatin states to persist through generations of cell divisions and to spread on DNA. During their subsequent development, immunostaining for spot 35 protein demonstrated the rearrangement of the Purkinje cells into a single row and the maturation of their somata, axons and dendrites. A validated questionnaire, which was self-administered, anonymous and filled in under supervision during October 1994.

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Two investigators independently extracted data on patient population, methods and results. The article presents main results of the open randomized investigation of the effectiveness and safety of the new non-depolarizing myorelaxant Nimbex included in the composition of anesthesiological maintenance of thoracal operations of high risk.

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Differentiation between malignant B-cell lymphomas and pseudolymphomas of the skin. This study shows an increase in unacylated acylated ghrelin and unchanged acylated ghrelin after a 12-week combined exercise programme in overweight children. Effects of contraceptive steroids on the pharmacodynamics of ethanol in rats. In conclusion, TGF-beta1 triggers apoptosis in MEC through mitochondrial pathway involving: activation and translocation of Bax to mitochondrial membranes, release of cytochrome C from mitochondria, activation of CPP-32 and degradation of its substrate - PARP in the nucleus. Sex, initial age, incidence and appearance of the 1st articular localization in 500 cases of rheumatoid disease

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Tenodesis of subclavius in the treatment of recurrent dislocation of the sterno-clavicular joint. Flutamide-induced acute hepatitis in advanced prostate cancer patients. Pulmonary perfusion measured by means of electrical impedance tomography.

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Food-Restriction Lowers the Acoustic Startle Response in both Male and Female Rats, and, in Combination with Acute Ghrelin Injection, Abolishes the Expression of Fear-Potentiated Startle in Male Rats. Cows were blood sampled once per week precalving and once in the week following calving, at the same time of day and the same day of the week.

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Diagnosis was based on case history along with a clinical picture and presence of antibodies against Borrelia burgdorferi, using ELISA test (Borrelia IgM and Borrelia IgG recombinant Biomedica). The infectivity of SARS is related to the degree of closeness of contact with the patient. Similarly, the N-terminal region of 3-OST-3(A) was fused to the sulphotransferase domain of 3-OST-1 to generate N3(A)-ST1. Immunological and regenerative aspects of hepatic mast cells in liver allograft rejection and tolerance. On the other hand when acetylcholine is present in the subphase of phosphatidylcholine monolayer the velocity of HSA penetration in these monolayers in sharply decreased.

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In case of Tween 80, Labrasol, and PVP K-30, the flux of ketoprofen decreased as the loading content of the additives increased. p16 and p53 frequencies increase from benign to borderline and malignant tumors, similarly to previous reports, possibly reflecting the accumulation of inactive mutant protein. Effects of metal ions on the binding activity of the human leukocyte leukotriene B4 receptor. Expression of cell surface hydrophobicity and adherence was greatest in the O type followed by the R and then the W type and finally the S type. Western blot analysis showed that the expression levels of Galphai, Galphao, Galphas, Galphaq and Gbeta were the same in the brains of mice of both genotypes.

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An unusual cause of obscure gastrointestinal bleeding in a patient with cirrhosis. Genetic and pharmacological rescue experiments identified c-Jun as a key substrate of Fbw7 in controlling progenitor cell viability, whereas inhibition of Notch signaling alleviated the block in stem cell differentiation. Mural thickness and appearance of the right dorsal colon were determined from ultrasonographic images obtained at right intercostal spaces 10, 11, 12, 13, and 14. Herpes simplex encephalitis is an infrequent infection with high mortality and morbidity.

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Characteristics of protectant synthesis of infective juveniles of Steinernema carpocapsae and importance of glycerol as a protectant for survival of the nematodes during osmotic dehydration. Zurich regulations for radiometry in conventional roentgen therapy, in megavolt therapy and in problems of radiation protection Cysteine-rich secreted protein-1 (Crisp-1) is a major androgen regulated protein in the epididymal lumen fluid of the rat and other species. In-person interviews took place with a representative sample of 916 noninstitutionalized older adults. Analysis of variance has been carried out for the diglyceride content of each region in an attempt to detect possible differences in the diglyceride levels among the various regions.

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CWF-145, a novel synthetic quinolone derivative exerts potent antimitotic activity against human prostate cancer: Rapamycin enhances antimitotic drug-induced apoptosis through the inhibition of Akt/mTOR pathway. This study shows the capacity of the repeated sequence pattern comparison to be used as a tool for confirming taxa status, (taxinomic classification is a primary determinant of management priorities for endangered species, neglect of distinct taxa may lead to their extinction), and for inferring phylogenetic relationships among related species.

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Several pharmacological blocking drugs and other inotropic agents did not potentiate or block the inotropic response to glucagon. We conducted a two-year, double-blind, placebo-controlled, randomized clinical trial involving 276 healthy participants, 65 years of age or older, with plasma homocysteine concentrations of at least 13 micromol per liter. Therapeutic modalities included suspension traction for two, femorotibial external fixation for two.

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Comorbidities included concurrent diagnosis of major depressive disorder and/or posttraumatic stress disorder. C14 studies in carbohydrate metabolism: glucose pool size and rate of turnover in the normal rat. Extensive dendritic sprouting induced by close axotomy of central neurons in the lamprey. A comprehensive review of the pediatric overweight literature was undertaken to examine secular changes in the prevalence of pediatric overweight, the current magnitude and scope of pediatric overweight, and the identity of high-risk groups in the U.S.

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In three studies, athletes judged the actual or hypothetical supportiveness of various coaches. Probes consisting of red and line stimuli presented separately were used during the course of fading to assess control exerted by each element of the compound. In these patients, the diagnosis of SIADH is confirmed in the course of treatment.

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The findings on ultrasound were compared with the results of the histological specimens in group 1. Utility and reproducibility of semiquantitative analysis of sestamibi breast images. Simultaneous analysis of multiple cytokines in the vitreous of patients with sarcoid uveitis. The RCV is measured using the tracer sodium fluorescein (SoF) and the PV with the dye indocyanine green (ICG).

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The Moosmann-Behl hypothesis of statin-induced muscular and neuronal damage mediated by oxidative stress might explain at least partially the pathogenesis of mevalonic aciduria. Receiver operating characteristic (ROC) analysis was performed to determine the optimal echocardiographic end-diastolic diameters of the right ventricle, the ratio of the right ventricle to left ventricle (RV/LV ratio) on CTPA, and NT-proBNP and Tn-T cut-off levels with regard to prognosis.

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Promotion of exercise and prevention of becoming housebound are important for improving life prognosis. Operative treatment for non-union of the carpal scaphoid bone with a small proximal fragment often presents some difficulties. This contributes to an overall limited use of existing electronic resources that inhibits evidence-based practice. Transient expression of AtNCED3 and AAO3 genes in guard cells causes stomatal closure in Vicia faba.

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PWS individuals show a specific cognitive deficit in task switching which may be associated with the display of temper outbursts and repetitive questioning. Biomedical predictors included biomedical risk, mucositis, the mode of transplantation, total body irradiation, age and gender. Slalom chromatography (SC) is used for the separation of large double-stranded DNA molecules.

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Increasing the density of endothelial or smooth muscle cells in culture increased cell-cell contact and decreased cell spreading, leading to growth arrest. Our results show, for the first time, that ceramide derived from de novo synthesis is an alternative mechanism to sphingomyelin hydrolysis in the BCEC death process initiated by TNF-alpha/CHX. Once reseeded on the denuded parietal peritoneal surface of syngeneic recipients, these TM-transfected MCs continued to express TM antigen in vivo for at least 90 days.

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sp., parasite of Oryzomys palustris (Mammalia) of the United States Large scale epidemiological studies suggest that hormone replacement therapy (HRT) reduces cardiovascular events in postmenopausal women. The temperature near the carotid artery has been measured in the unrestrained pig by means of radiotelemetry. Access site complications with carotid angioplasty and stenting.

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Strata of connective tissue were found to divide the smooth muscles of the proximal two-thirds of the female urethra into 3 layers. rubrovaria as vector of Trypanosoma cruzi were evaluated: patterns of (i) feeding, (ii) defecation, and (iii) resistance to starvation, using insects fed on mice. Clinical manifestations, other than erythema migrans for Lyme borreliosis, do not provide strong diagnostic clues. But eight days after admission, abdominal pain abruptly became worse again. Recent findings suggest the involvement of the cerebellum in perceptual and cognitive tasks.

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Infection with influenza a virus leads to flu antigen-induced cutaneous anaphylaxis in mice. Comparative results of combined procedures for glaucoma and cataract: II. Sphincter-saving resection, or not, for cancer of the midrectum. In the in vitro infections of white-tailed deer erythrocytes, the EHD and BT viruses were associated with pits in the erythrocyte membrane. Yeast tRNAPhe was deuterated at the purine C(8) positins by heating in 2H2O and also biosynthetically.

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Rationale for the use of somatostatin analogs as antitumor agents. Epidemiologic implications and significance of these results for cancer control were discussed.

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Accumulation of alpha-ketoisocaproate from leucine in homogenates of tissues from rainbow trout (Salmo gairdnerii) and rat. Evaluation of a novel biphasic calcium phosphate in standardized bone defects: a histologic and histomorphometric study in the mandibles of minipigs. All these cases were studied conventionally including history, physical and neurological examination in addition to investigations with particular emphasis on connective tissue screen and thyroid function test. More importantly, the CP can facilitate home terminal care when necessary. Microporous expanded polytetrafluoroethylene (PTFE) has recently been proposed as an arterial graft.

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To investigate whether miR-181b regulates tissue inhibitor of metalloproteinase-3 expression and affects atherosclerosis and aneurysms. Its diagnostic value consists in that symptoms, recurrences and metastases detectable by its application develop at an earlier stage than those detected by X-ray techniques and before clinical manifestations of the disease. Measurements of scapular position and rotation: a reliability study. Nucleus pulposus samples were surgically obtained from 8 patients with degenerative lumbar disc disease. Postmortem striatal tissue was examined from normal controls (NC), chronic paranoid SZs (SZP), and chronic undifferentiated SZs (SZU).

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To highlight outcomes in compassionate care, this paper uses case studies from two participating services. Recent studies suggested a potential role of podoplanin in certain tumor cells. Patient compliance is important regardless of the type of treatment selected. The need for a culturally-tailored gatekeeper training intervention program in preventing suicide among Indigenous peoples: a systematic review.

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SFP genes also show evidence of lineage-specific gene loss and/or gain. To analyse the prevalence and clinical significance of anti-cyclic citrullinated peptide antibodies (anti-CCP) and antikeratin antibodies (AKA) in patients with palindromic rheumatism (PR).

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All of these patients had resection of their lesions with no change in their neurological status. Data sources can be: speaking and singing voice, sound, pictures (X-ray, CT, MR, ultrasound, voice range profile, audiogramm), video signals (stroboscopy, cinematography, intraoperative pictures) and written information (computer presentations) in all combinations. Iodine is essential especially for the synthesis of thyroid hormones that regulate the cellular metabolism of the whole organism. In the rabbit iliac artery, polyhydroxybutyrate stents caused intensive inflammatory vascular reactions which ban them from clinical use. Accuracy of Bayesian, Sawchuk-Zaske, and nomogram dosing methods for vancomycin.

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Samples of ejaculated sperm from idiopathic asthenozoospermia patients and normozoospermic men were separated and purified by Percoll discontinuous density gradients, the distribution and expression of SEPT4 in the sperm samples were determined by immunocytochemistry, and the expressions of SEPT4 mRNA and SEPT4 protein were detected by RT-PCR and Western blot. These studies indicate the potential of oligonucleotide-based therapies for modulating cardiac miRNAs and validate miR-208 as a potent therapeutic target for the modulation of cardiac function and remodeling during heart disease progression. These difference equations describe the time-evolution of clusters of individual agents that are grouped by discretizing the state space. Molecular biological methods (DGGE) as a tool to investigate nitrification inhibition in wastewater treatment. The response to visual stimuli was localized to occipital cortex.

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This study examined whether variation in HPA axis activity underlies the association between mood symptoms and cognitive functioning. Of the grading systems evaluated, Histologic Risk Assessment demonstrated the best results for survival prediction in oral squamous cell carcinoma. Spatial patterns of cystic fibrosis mutation spectra in European populations. Acid cysteine proteinase in the eggs of the silkmoth, Bombyx mori, exists as an inactive proenzyme.

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Treatment of astrocytes with heparitinase indicated that the growth-inhibitory action of medial astrocytes may depend heavily on HS by an as yet unknown mechanism. A 46-year-old man complained fever, headache, and vertigo after he was given steroid for sudden deafness. The effect of protein aggregates on the aggregation of D-glyceraldehyde-3-phosphate dehydrogenase (GAPDH) during unfolding and refolding has been studied. Production of HLA antibody in mice immunised with syngeneic mouse-human hybrid cells containing human chromosome 6. Comparative studies on the incidence of suicide in the 2 German states

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The literature is reviewed for all reported cases of ossified ligamenta flava causing myelopathy in Caucasians. Furthermore, binding of the VP16 activation domain may promote TFIIBc conformations primed for binding to a TBP-DNA complex. Although, its targeting with nonsteroidal antiinflammatory drugs (NSAIDs) and COX-2 selective inhibitors has been investigated for years with promising results at both preventive and therapeutic levels, undesirable side effects and the limited understanding of the regulation and functionalities of the COX pathway compromise a more extensive application of these drugs. The effect of gastric ischemia-reperfusion (GI-R) on gastric mucosal cellular apoptosis and proliferation was investigated using histological, immunohistochemical methods in Sprague-Dawley rats.

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Tracing of r2-specific progenies of Hoxa2 expressing cells indicated that the control of inspiratory activity resides in rostral pontine areas and required an intact r2-derived territory. The authors chose a solution consisting of seven clusters: (1) personal and professional stressors, (2) organizational climate, (3) job insecurities, (4) rationalizations A, (5) personal inhibitions, (6) rationalizations B and, (7) personality factors. Beyond type 2 diabetes: the need for a clinically useful way to identify insulin resistance.

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These studies showed a 10 to 25 percent turnover of aflatoxin Q1, with the subsequent formation of five metabolites. Specification of the nature of these processes may prove to be complex, as post-hoc inspection of the data suggested that for the spatial cue condition, the alternating-switch cost may oscillate between cost and benefit, depending on the relevant task.

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Unlike small peptide substrates, glycosylation of the OID was dependent upon its interaction with the first 6 TPRs of OGT. The role of natural indigo dye in alleviation of genotoxicity of sodium dithionite as a reducing agent.

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Data frequency at each station on a monthly basis identified the spatiotemporal distribution for the first time in the study area. In situ polymerization of 3-glycidoxypropyl trimethoxysilane (GLYTS) as a new tool for stone conservation. Combination of chlorprothixene and phenoperidine in peripheral surgery The conductivity of cytoplasm, plasma membrane, and inner wall region were found to vary with medium ionic strength from 9 to 12 mS cm-1, 5.8 nS cm-1 to approximately 50 nS cm-1, and 6 microS cm-1 to 240 microS cm-1, respectively.