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Tn10 mutagenesis revealed the following order of genes in the fru operon: fruB-(fruK, fruF)-fruA. Data obtained while a horse was walking and trotting on the treadmill. In vitro studies with highly purified TlpA showed concentration and temperature dependence for both fully folded conformation and function, indicating that the thermosensing in TlpA is based on monomer-to-coiled-coil equilibrium.

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However, adding spatially structured extra-variability in the model fitted to the data when such extra-variability does not exist conditionally on the covariates included in the model (over-fitting) may bias the estimation of the ecological association between covariates and relative risks toward the null. Experimental data are strikingly compatible with bioinformatic predictions of the specific role and interaction of PCNA, CDC2, and CCNA2 at all phases of the cell cycle and of CHEK1 in regulating DNA repair and preservation. In both experiments, a greater stability and attractiveness was observed for LC stimuli, which suggests that in a (...)LCLC(...) flow, the listener could more naturally provide a segmentation into LC chunks. Meat Science and Muscle Biology Symposium: manipulating meat tenderness by increasing the turnover of intramuscular connective tissue.

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We have used a cell-free, DNA-dependent protein-synthesizing system to study the stimulation of phage P2 late gene expression by satellite phage P4. Neither the glycine nor the serine mutation at position 269 affects the ability of the enzyme to catalyze ATP synthesis from ADP and carbamyl phosphate. Among them, almost half are transliterated from foreign languages, and some of them are titled with India, Han region, etc. This study aimed to evaluate the prevalence of sleep problems in very old persons and its relation to physical and mental health and drug use.

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Searching for the second oxidant in the catalytic cycle of cytochrome P450: a theoretical investigation of the iron(III)-hydroperoxo species and its epoxidation pathways. Blood samples and conjunctival biopsies were taken from each patient. Three congested flaps with TcPCO (2) more than 90 mmHg were selected for intervention. MRI is currently required to derive an accurate measure of VAT at the individual level.

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Findings of a suprasellar round cystic mass with thin ring-enhancement on MRI associated with thickened stalk, hyperprolactinemia, and diabetes insipidus may be suggestive of a pituitary abscess. The renin-angiotensin system regulates blood pressure through its effects on vascular tone, renal hemodynamics, and renal sodium and fluid balance. When isolated from the vessel wall, quail aortic endothelial cells from embryonic day 11 embryos were able to colonize both host arteries and veins. We propose that the beneficial findings cannot easily be extrapolated to other patient populations since there is suggestion from clinical trials that the sickest patients, especially those with severest appearances of sepsis, shock and organ failure may not benefit or may even be harmed. Further studies showed that Bax and p21 protein expression was upregulated, whereas cyclin B1, Cdc-2 and Bcl-2 protein expression was downregulated.

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Prothrombin was assayed in 24 patients with liver cirrhosis both as activity and as antigen. The immune responses to fragment C seen in mice immunized with BRD937 are the strongest we have observed and indicate that the htrA promoter may be very useful for expressing foreign antigens in salmonella vaccine strains. Small-angle HeNe laser light scatter and the compressive modulus of articular cartilage.

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In ten of these interventions the number of participants was sufficiently large to quantitatively determine the effect of the intervention on loneliness. The other mAb reacted with two distinct molecules of approximately 65 and 60 kD, respectively. Moreover, misconceptions regarding PCS and CTE are also prevalent and likely reflect inconsistencies in the scientific literature, coupled with misleading media reports. Induction of the structural bceAB genes requires the BceR response regulator and the BceS histidine kinase of a signal transduction system.

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Mothers and offspring served as controls in two earlier studies: 101 children at age two years and 118 children at age eight years. There is increasing interest in using fructosamine measurements in screening for or managing diabetes, yet uncertainty remains as to whether these measurements should be corrected for variation in serum protein concentrations. There are volumetric and microstructural abnormalities of the thalamus in preterm children with PVL, very likely reflecting neuronal loss and myelinated axonal injury. This is the first evidence of a founder effect for a MYOC mutation in Spanish JOAG patients.

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These results show that obese women with male type of body fat distribution also have male characteristics of muscle mass, morphology and function. A statistical analysis of the reaction time to the noxious stimulus demonstrated that the responses of the acupunctured animals were not significantly different from those of the controls.

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To investigate the impact of prolonged HIV suppression on the immune system by analysing the expression of several lymphocyte surface markers in a group of HIV-1-infected patients who maintained undetectable HIV-1 RNA levels for more than 24 months. Interspecific variations in the morphology and ultrastructure of the rhabdoms of oplophorid shrimps. Assessment of the potentialities of the electrocommunication system of fishes

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Differences in the magnitude of SOC sediment fluxes, flux profiles, time trends within those profiles, and isomeric ratios suggest that SOC deposition in high-elevation ecosystems is dependent on regional upslope wind directions and site location with respect to regional sources and topographic barriers. Plasmodium falciparum: worldwide sequence diversity and evolution of the malaria vaccine candidate merozoite surface protein-2 (MSP-2). Our results provide new insight into a number of peculiar physiological and metabolic traits of B. The use of a handheld portable ultrasound machine was effective for patient management decisions in resource-poor settings, and decreased the need to triage selected patients to higher levels of care. Inguinal and axillary dermatitis in wallabies in north Queensland due to the dermanyssid mite Thadeua serrata.

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Previous studies have shown increased cessation rates for patients who accurately perceive that their ED visit is smoking-related. By intraperitoneal injection of tumour antigen specific CTLs into the LCI-D20, the preventive and therapeutic effects of these CTLs to HCC in the LCI-D20 model were assessed. Direct competitive inhibition enzyme-linked immunosorbent assay for determination of fumonisin B1 (FB1) in corns were developed by using anti-FB1 monoclonal antibody.

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Systematic review of available evidence-based interventions and implications for Italy. In vitro exposure of Gram-negative bacilli (GNB) to antimicrobial agents may induce endotoxin (ET) release, that may cause various reactions in vivo resulting in endotoxic shock. Elevated CK levels are associated with severe oligospermia, irrespective of the clinical diagnosis. Blood concentration curves alone are of limited value and give less than satisfactory information about CSF distribution spaces and were corrected for albumin disappearance from the blood to other compartments.

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The spatial resolution of digital radiographs was well below that of the spot films, while no difference was found in contrast resolution. We examined the binding of peripheral blood mononuclear cells from various primate species to a panel of monoclonal antibodies with specificity for human T lymphocytes. We conclude that NO from an iNOS source is not essential for the regulation of sodium excretion and BP in the presence of a high-salt diet in a normal rat. Efficacy of lorazepam and haloperidol for rapid tranquilization in a psychiatric emergency room setting. Inhibition of extracellular signal-regulated kinase in liver of hyperhomocysteinemic mice.

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After the binding of IgG to the surface Fc receptor of Schistosoma mansoni schistosomula, the Fab portions of IgG are cleaved and small peptides are liberated in the culture medium. Our objective was to assess the risk of stroke (by subtype) in contemporary patients with RA, particularly in relation to time since RA diagnosis. Directed, cytodiagnostically controlled hormone therapy in prostate carcinoma The CEM clones, MOLT-4 and HL60/SN3 cell lines expressed functional or measurable p53 protein, while the other cell lines did not. A randomized trial with half of enrollees receiving intensive care management services and half receiving usual care.

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Our experiments demonstrated that rectal palpation is a potential cause of BLV spread in herds and that detection of BLV proviral DNA in cattle by PCR is useful screening test for early diagnosis of BLV infection. On the biochemistry of drugs influencing the monoamine metabolism in the brain Paediatric community-acquired pneumonia: current concept in pharmacological control. The attributable fraction of HIV-infected tuberculosis cases was estimated from the prevalence of HIV infection in tuberculosis cases and the prevalence of HIV infection in women attending antenatal clinics.

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Endothelium-dependent relaxation to acetylcholine was tested in aortic rings from nondiabetic age-matched control, untreated diabetic, and insulin-treated diabetic rats to evaluate endothelial function. A general problem in immunocytochemistry is the development of a reliable multiple immunolabeling method when primary antibodies must be used that originate in the same species.

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The efficiency of each aeration method was evaluated by monitoring the evolution of parameters such as temperature, moisture content, CO(2) and O(2) ratio in the material and dry material losses. Study of revascularization of autogenous cortical bone grafts in rabbits using radiophosphorus.

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A new species, Pythium bifurcatum, isolated from soil samples taken from a wheat field in Lille in northern France is described here. The case histories of the 44 ventilated spinal cord damaged patients who have been treated at the Mersey Regional Spinal Injuries Centre prior to 1985 were reviewed. Tpx2 and Aurka expression decreased whereas phospho-Aurka increased in Bcl2l10 RNAi-treated oocytes. Added to this is the significant morbidity and mortality from cerebral oedema associated with acute stroke, hypoxic ischemic coma, neurological cancers and brain infection.

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Exclusive focal Tc-99m V-DMSA uptake in this clinical setting could be considered as a sign of effectively treated lesions and not a sign of deterioration. Adhesion-related signal transduction is important throughout development, hemostasis, immunity, and in diseases such as cancer. So far, few cases have been reported of carbamazepine-induced lupus erythematosus within months after the start of treatment. However, we believe that this tumor may be underdiagnosed in adults owing to its similarity to clear cell (conventional) carcinoma and in some cases to papillary renal carcinoma.

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In posttreatment BMB samples, nonresponders had a significantly higher frequency and grade of fibrosis and higher values of MVD, total vascular area, and plasma cell percentage. IL-12 therefore initiates a cascade of events in B cells, including STAT4 activation, IL-12Rbeta2 up-regulation, IFN-gamma production, and T-bet up-regulation, potentially leading to Th1-like differentiation.

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The tumor also led to development of mucocele in the frontal sinus not yet fully developed as on opposite side. Reoperative correction of previous pelvioureteral plastic surgery. Progestin, estrogen, and insulin-like growth factor-I stimulate the prolactin receptor mRNA in human endometrial stromal cells. Early-stage metastasis is regulated by multiple factors within tumor cells as well as by the tumor microenvironment (TME). Importantly, electrophysiological data showed a significant amplitude modulation of the N2pc time-locked to target onset as a function of cue--target spatial congruence.

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Thus, we confirmed that high LET heavy ions are significantly more effective than X-rays for the induction of in vitro cell transformation. We next assessed the possibility of performing the prepurification step by high-speed centrifugation (50,000 x g for 80 min) of 1.5-ml pools containing 25 microl of 60 individual serum samples, of which only 1 contained HIV-1 RNA (centrifugation Amplicor assay). Oral clonidine 2.5 and 5.0 microg/kg premedication decreases the propofol concentration required for loss of consciousness. The effects of song familiarity and age on phenomenological characteristics and neural recruitment during autobiographical memory retrieval.

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This monomeric state was also produced at the lower PKA concentration and physiological ionic strength. Impact of new mutations in the methylenetetrahydrofolate reductase gene assessed on biochemical phenotypes: a familial study. Operative findings included compression of the nerve at the intermuscular septum or at the entrance to the cubital tunnel, dense scarring after intramuscular transposition, and constriction by fascial slings.

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The complex isolated from these mutants contained N2 although in diminished amounts. The post-operative courses of both patients were long (85 and 40 days respectively) and difficult. He had a concomitant 65-mm AAA and a 48-mm right common iliac aneurysm. The preclinical and epidemiological evidence regarding chemoprevention with selenium and vitamin E were reviewed. When perfused at venous flow, melanoma cells arrested abruptly and began to spread immediately.

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Despite a different environment, no severe graft-vs.-host reaction occurred and engrafted T lymphocytes became functional. In this study, isolates of this bacterial species were tested for the production of bacteriocin-like inhibitory substances (BLIS).

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High-performance liquid chromatographic analysis of tamoxifen and major metabolites in human plasma. Here we report that after removal of the SN cell body, isolated SN synapses of Aplysia in culture express protein-synthesis dependent long-term facilitation (LTF) produced by 5-HT that decays rapidly.

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Effect of calcium antagonist compound nisoldipine on transepithelial electrical parameters in the isolated frog cornea. Clinical effect of aminobenzyl penicillin (cilleral) injection in gall bladder diseases MOLT-4 cells and MOLT-4/DNR cells were similarly sensitive to the apoptosis-inducing effect of As(2)O(3). Effect of lipid-lowering therapy on the progression of renal disease in nondiabetic nephrotic patients. From schools to community learning centers: a program evaluation of a school reform process.

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Responses to the first six tilts (positive stimuli) were reinforced on a variable-interval one-minute schedule, whereas responses to the other six tilts (negative stimuli) were extinguished. It was found that in most of the age-related functions studied changes were delayed or partially prevented by food restriction. Two- to five-fold higher concentrations of glucagon are required for half-maximal stimulation of adenylate cyclase when the hormone is complexed with dimyristoyl phosphatidylcholine, dipalmitoyl phosphatidylcholine, or bovine brain sphingomyelin. Specifically, do voice-specificity effects in implicit memory depend on information in a perceptual representational system or, alternatively, on the similarity of study and test exemplars? From recognition to responsibility: Josef Warkany, David Smith, and the fetal alcohol syndrome in the 21st century.

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A randomized, prospective study should be performed to analyze the safety of abandoning this practice. These results suggest that although controlled penetration and diffuse excitotoxicity may induce similar temporal and cellular patterns of hsp72 expression, the spatial location of hsp72-immunoreactive cells may differ between the two models. Methionine-requiring and pantothenic acid-requiring auxotrophs of Rhizobium japanicum USDA 31, as well as highly antibiotic-resistant mutants of R. On the anatomo-pathological changes due to permanent intracardiac stimulation.

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Physiological basis for a regime for children in the 3d year of life Ectopic expression of a form of STAT3, STAT3C, rescued U266-1984 cells from IFNalpha-induced apoptosis. The aim of this study was to correlate computed tomography (CT) findings with pathology in gastrointestinal stromal tumors (GISTs). We investigated whether increased HDL cholesterol induced by adenoviral human apoA-I (AdA-I) transfer increases number and function of EPCs, promotes incorporation of EPCs in Balb/c allografts transplanted paratopically in C57BL/6 ApoE-/- mice, and attenuates transplant arteriosclerosis. Findings from the questionnaires showed the young people with CP in both age groups to be socially less active than the controls.

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Now that PGs (prostaglandins) are becoming more available for the induction of labor and the termination of pregnancy, it is not surprising that some adverse effects to these very potent substances are occurring, especially in patients with preexisting disease. The Beck Oral Assessment Scale and the mucosal-plaque score were used to assess the oral cavity. Solubility increases on the order of 2-5 were simulated for methylnaphthalene and dimethylnaphthalene, respectively.

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This preferred Ta did not change until the specific absorption rate (SAR) at 2,450 MHz exceeded approximately 7.0 W X kg-1. An Overview on Novel Microbial Determination Methods in Pharmaceutical and Food Quality Control. Effects of low level exposure to lead on other measures of testicular function cannot be ruled out. COX-1 and COX-2 expression in stage I and II invasive cervical carcinoma: relationship to disease relapse and long-term survival.

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Third, from the localizations of conserved residues in the subunits comprising the rotors of ATP synthases, we suggest that the conserved interaction site at the interface of subunit c and delta (mitochondria) or epsilon (bacteria and chloroplasts) may be important for connecting the rotor of F1 to the rotor of F0. To identify the main barriers to achieving comprehensive population coverage. The stimulated Jurkat cells simultaneously released evident eosinophil chemoattractant activity (ECA).

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Transplacental hemorrhage during voluntary interruption of pregnancy. The T cell factor transfers the ability to elicit an antigen-specific immediate hypersensitivity-like ear-swelling reaction following local challenge with antigen.

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Posterior-only unit rod instrumentation and fusion for neuromuscular scoliosis. Molecular mechanisms underlying the long-term impact of dietary fat to increase cardiac pyruvate dehydrogenase kinase: regulation by insulin, cyclic AMP and pyruvate. The endogenous thrombin potential (ETP) represents the balance between pro- and anti-coagulant forces operating in plasma and can be used to investigate hyper- and hypo-coagulability. Thus sensory information related to the local frictional condition at the respective digit-object interfaces controlled the normal force at both digits.

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Donor lymphocytes were obtained from lymph nodes, enriched for T lymphocytes and labeled in vitro with 5-(3H)uridine. An alternate control strategy is based upon reducing the gas exchange mismatch by manipulation of those environmental parameters known to affect plant or algae gas exchange ratios. Enzyme activity was monitored by measurement of released fatty acids using capillary GC-MS. Side-to-side choledochoduodenostomy in the management of choledocholithiasis.

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Proteome, salicylic acid, and jasmonic acid changes in cucumber plants inoculated with Trichoderma asperellum strain T34. Vocal cord palsy after vincristine treatment in a child and the inefficacy of glutamic acid in the prevention of relapse: a case report. Little is known about the comparative effectiveness of atypical antipsychotics in long-acting injection formulation.

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However, Ldb4b binds to LMO4 via Ldb4a when coexpressed in culture cells. Assessment of plasma neopterin in clinical kidney transplantation. In vivo stimulation of sympathetic nervous system modulates osteoblastic activity in mouse calvaria. Rotary shadowing and immunogold staining of the collagen VI microfibrils and isolated tetramers indicated that betaig-h3 was specifically and periodically associated with the double-beaded region of many of the microfibrils and that this covalent binding site was located in or near the amino-terminal globular domain of the collagen VI molecule. Suggested improvement of visual acuity: a statistical reevaluation.