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The developing queens in colonies treated with as little as one coumaphos-impregnated strip for more than 24 h suffered a high mortality rate. Our hypothesis is that maternal thyroid function in the first trimester is altered in pregnancies that subsequently deliver small for gestational age (SGA) neonates. Mammary adenocarcinoma 16/c tumor-bearing mice were treated with an i.v.

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Chemosensivity is augmented in HF, correlates with increased pulmonary ventilation (VE), and is an adverse prognostic marker. Since then, several studies documented that smoking is nephrotoxic in patients with diabetic and non-diabetic renal disease. Positron emission tomography using fluoro-deoxyglucose (PET-FDG) imaging has been shown to be effective in detecting and staging malignancies based on tumor glucose metabolism.

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Frequently, HHs cause central precocious puberty (CPP) and/or gelastic seizures. We have been involved for the past several years with the development of a method for the localization of mRNA in individual cells using hapten labeled cDNA. The histological changes produced consisted of mild congestion and inflammatory change in the jejunal and ileal mucosa and dilatation of the crypts and capillary dilatation in the large intestinal mucosa. At surgery, significant involvement of the entire gastrointestinal tract from the gastric antrum to the sigmoid colon was found. The main lesions in the brain were those of acute focal hemorrhagic encephalomalacia.

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This non-operative management in our patients allowed healing of bile duct injuries without any stricture, at 2 years follow-up. The basic helix-loop-helix transcription factor TAL1 (or SCL), originally identified from its involvement by a chromosomal rearrangement in T-cell acute lymphoblastic leukemia, is required for hematopoietic development. The aim of this study was to compare retrospectively the longterm functional results of straight or J-pouch coloanal anastomosis and low colorectal anastomosis in patients operated for rectal carcinoma. Further studies are needed to identify the factors linked to these benefits and their time course.

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Biosphere II-scheduled for completion in March 1991-will be essentially isolated from the existing biosphere by a closed structure, composed of components derived from the existing biosphere. P-glycoprotein does not seem to be involved in the poor response to steroid treatment seen in some pemphigus patients. Juvenile hormone (JH) biosynthesis is inhibited under short-day conditions in the brown-winged green bug Plautia stali.

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rubescens filaments orally applied to coregonids and to discuss the findings in the context of microcystin toxicity previously reported in carp and trout. In this article we consider two coupled tetrameric mixed-valence (MV) units accommodating electron pairs, which play the role of cells in molecular quantum cellular automata. This effect is particularly evident for less experienced surgeons. Data on intense storms that caused severe flooding within the catchment (and also all over Belgrade and other parts of Serbia) in June and July 1999 are used for comparison of design flows with a real event. Role of the cytoskeleton in the spreading process of epithelial cells

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These geodesics and geodesic distances provide a framework for optimally matching, deforming, and comparing shapes. Management of an anterior mediastinal pheochromocytoma causing tracheomalacia. These observations suggest that a hypoxic stimulus occurring in emphysema may be a novel mechanism that contributes to enhanced expression of PLTP. A comparative study demonstrated the efficiency of the above fraction in the RAST technique in distinguishing between Onchocerca volvulus-infected patients and those infected with other human filarial worms or other helminth parasites. Effect of temperature on the dilatation capacity of the isolated frog heart ventricle before and after work

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Trial design and reporting standards for intraarterial cerebral thrombolysis for acute ischemic stroke. Thus, a more efficient and comfortable therapy can be achieved for patients in need of CP treatment. The daf-19c isoform is expressed in all ciliated sensory neurons and is necessary and sufficient for activating X-box containing ciliogenesis genes. The role of the Chronobiology and Chronomedicine Problem Board of Russian Academy of Medical Sciences in the development of internal medicine (on the occasion of its 25th anniversary) Relationship between blood groups ABO and clinical features of duodenal ulcer

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Lung cancer susceptibility: are we on our way to identifying a high-risk group? Characterization of an amino-acid substitution leading to spectinomycin resistance in Escherichia coli. Effect of peritoneovenous shunting with the Le Veen valve on ascites, renal function, and coagulation in six patients with intractable ascites.

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Prevalence of pathological internet use among adolescents in Europe: demographic and social factors. The shape of the resulting phase-response curve closely matched the phase-shifting effects of light pulses, and its amplitude was dependent on the amount of the injected peptide. To evaluate the effect of three psychological treatments on the mother-child relationship and child outcome. Other possible sources of human tear lactoferrin were considered, but we concluded from our data that the primary source of lactoferrin in normal human tears is the acinar epithelium of the main and accessory lacrimal glands. Bacteria with interference capability of potential respiratory pathogens can prevent colonization and subsequent invasion by these organisms.

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The expression of GalNAc-T3 was evaluated immunohistochemically in 106 paraffin embedded samples from surgically resected colorectal carcinomas and was related to patient and tumor characteristics. To characterize the microbial etiology of chronic suppurative otitis media comparing the methods of classical bacteriological culture and polymerase chain reaction. Dynamics of apoptosis in the ovarian follicle cells during the late stages of Drosophila oogenesis.

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Accordingly, circular dichroism spectroscopy and fluorimetry analysis indicated that CBD1 but not CBD2 could adopt a defined secondary structure and form a complex with a peptide corresponding to the caveolin-1 scaffolding domain, which is the site of interaction of caveolin-1 with various proteins. Suicidal behavior in the remote past seemed as predictively important as suicidal behavior during follow-up. Partly contradictory results and conclusions are most likely caused by technical limitations, limited number of studies and small sample size. This shortage may be at least in part due to insufficient training opportunities.

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ECG showed prolonged QT interval and macroscopic T Wave alternans. The SUMO conjugation system plays an important role in specific protein expression.

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In order to obtain information concerning the binding site of urokinase (EC 3.4.99.26) the inhibitory action of aliphatic ammonium and amidinium ions has been studied. Weber-Christian panniculitis with membranous glomerulonephritis.

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The binding of 125I-labeled hGAP 1-56 to all three antisera was displaced completely by unlabeled hGAP 1-56. For direct electrical current a stronger impact was observed at low flow rate than at higher flow rate. Alcoholism, heroin dependency, and methadone maintenance: alternatives and aids to conventional methods of therapy. We found that GPI 1046 had potent neuroprotective effects in this model.

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Bullous diseases of the oral mucosa and skin were originally classified on the basis of clinical and histological criteria. Chikungunya virus neither stimulates the replication of densovirus nor is its own replication suppressed due to co-infection. The potential risks versus benefits of phenylephrine administration should be evaluated carefully, especially In old horses. Nuclear maturation to meiosis II in absence of cytokinesis resulted in significant increases in polyploidy. Eighteen episodes of sepsis associated with neutropenia were treated with 149 granulocyte transfusions.

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We also observed that fexinidazole and fexinidazole sulfone are more effective than benznidazole and nifurtimox as curative treatments, particularly for acute stage infections, most likely as a result of the higher and more prolonged exposure of the sulfone derivative. The frozen section quality of lung tissue was excellent after simple inflation with diluted embedding medium (2:3). In addition, some extracellular microbial pathogens, such as Pneumocystis carinii, may also interact with host cells via caveolae. The varus deformity appeared to originate from two muscles: the tibialis posterior in 9 cases and the tibialis anterior in 1 case. The plasma folate was found to interact with urinary arsenic profiles in affecting the UC risk.

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To study the effects of palmitoylethanolamide (PEA), a fatty acid ethanolamide, on aqueous humor outflow facility. Provision of services and care for HIV-exposed infants: a comparison of maternal and child health clinic and HIV comprehensive care clinic models. Immunochemical evidence for hybrid sialoglycoproteins of human erythrocytes.

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However, the level was lower than expected, and secretion was suggested to be a bottleneck. A number of other drug interactions have been reported in preliminary studies for which clinical significance has yet to be established. The spongiform changes increased mildly between week 8 and week 10 and remained essentially the same in subsequent weeks. A 21-year-old male soldier was admitted due to a sore throat, headache, generalized lymphadenopathy and persistent fever for 12 days.

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Effects of etofibrate on platelet function: in vitro studies in human plasma. Predictors for the development of tardive dyskinesia (TD) have been studied extensively over the years, yet there are few studies of predictors of the course of TD after it has developed.

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In its current form, the equation holds promise for understanding cognitive individual differences that could underlie practice variation. IgG4 antibodies to milk and egg are common in children and adults and are more common in children with asthma than in nonallergic children less than 3 years of age. This automated external defibrillator algorithm has high specificity and sensitivity when used in infants and children with either sternal-apex or anterior-posterior lead placement. To assess the effects of incorporating EBT as a motivational factor into a cardiovascular screening program in the context of either intensive case management (ICM) or usual care by assessing its impact over 1 year on a composite measure of projected risk. That action, however, is mediated via the receptor for insulin-like growth factor (IGF-I).

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The American College of Radiology (ACR) Breast Imaging Reporting and Data System (BI-RADS) is the product of the initial collaboration between various committees of the ACR and several other organizations, such as the American College of American Pathologists and the American College of Surgeons. The requirements for spindle assembly in Drosophila male meiotic cells are diametrically opposed to those of somatic cells. More importantly, this study indicates that protection with postconditioning is still apparent 1 week following reperfusion, suggesting long-term protection. The purposes of this study were to identify the P450 enzyme (CYP) responsible for zonisamide metabolism in humans by using expressed human CYPs and to predict drug interaction of zonisamide in vivo from in vitro data.

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Maternal smoking rates also declined for all race and ethnic groups in the 1990s, but important differences persist. Behavior disorders in a child cured of tuberculous meningitis with streptomycin Factors regulating muscle determination, differentiation and development have so far mostly been studied in vertebrates with external bilateral symmetry.

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Male Wistar rats were administered 10 mg/kg of 2C-B hydrochloride orally, and 24 h urine fractions were collected. The ERp29 expression profile largely paralleled that of protein disulfide isomerase (PDI), the closest relative of ERp29, consistent with a role in secretory protein production. Disopyramide was given as ordinary capsules (q.i.d.) or as a slow release preparation (b.i.d.) in a total dose of 600 mg per day. Post-operative pathological findings revealed IPMN was adenoma with mild atypia, and solid tumor was diagnosed invasive ductal carcinoma with solitary minute liver metastasis.

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Haploid slg1 deletion strains are sensitive to caffeine, as expected for mutants in the Pkc pathway, as well as a variety of other drugs. We report an unusual postoperative complication (hepatic laceration) in a child with type 3 vWD, who has not received any prophylaxis. Overall 6 patients, including 3 that did not undergo surgical treatment, died and 3 patients survived.

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Multicentre collaboration in 162 tissue-typed renal transplants. A case-control analysis was performed using claims from years 1998-2004. The cardiovascular response to stimulation by sympathomimetic agents before, during, and after exposure to simulated microgravity was determined in healthy volunteers equilibrated on normal or high sodium diets in order to further the understanding of the deconditioning process. The hepatic triglyceride (TG) concentration and the volume of cytoplasmic lipid droplets, presumably TG, as well as the serum TG concentration, increased only in the drug-treated RB rats.

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Increased expression of cystic fibrosis transmembrane conductance regulator and NKCC1 was also observed in EIEC or SD-infected cells vs. Preliminary results of myelobromol treatment of chronic granulocytic leukemia These results demonstrate the importance of timing of rhTPO in relation to chemotherapy and indicate that, by optimizing the timing, only two doses of rhTPO (one before and one after chemotherapy) were required to significantly reduce the severity of chemotherapy-related early thrombocytopenia. The current strategies of lymph node resection in gynecologic oncology have been presented. Our unique technique greatly decreased the risk of bacterial peritonitis in this patient with decompensated cirrhosis and associated ascites, which in this patient population results in a high mortality.

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Small interfering RNA-directed targeting of RON alters invasive and oncogenic phenotypes of human hepatocellular carcinoma cells. Experimental in-vivo and in-vitro studies on the effect of automobile exhaust and carbon monoxide on the cardiovascular system of mammals We hypothesized that the low-level somatic mutation observed in non-neoplastic tissues may be entirely or partially caused by inadvertent contamination by neoplastic cells during the surgical pathology gross assessment or tissue procurement process.

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Comparisons were made between adult (17-64 years of age) and geriatric (older than 65 years of age) patients and between patients with blunt and penetrating injury. Pericardial effusion in the neonate: a complication of umbilical catheters The relative response of EEG background activity to thiopental at different frequencies may assist lesion characterization as well as localization.

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This study sought to derive and validate an algorithm (expert system) to measure mean arterial pressure (MAP) lability. In the past 2 decades, the introduction of second-generation immunosuppressive drugs, such as tacrolimus, mycophenolate mofetil, sirolimus, and anti-interleukin-2 receptor monoclonal antibodies, has provided some alternatives to classic immunosuppressant choices. Critically ill pediatric patients are prone to hypophosphatemia, especially if they cannot be fed early by enteral route. This phenomenon was also noted when d-limonene-treated PaCa cells were stained immunohistochemically with anti-P21ras antibody.

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Interdisciplinary teamwork and international cooperation have been useful in the past and continue to be desirable. No pronounced side effects were observed in normal cells or mice. No statistically significant differences in postprandial hyperglycemia or patterns of glucose disposal were observed between the two routes of insulin delivery. Ibuprofen attenuated cardiopulmonary dysfunction by decreasing the early cytokine response.

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Outcomes of bladder exstrophy patients were studied in numerical terms using scoring systems for continence and health-related quality of life (HRQOL), along with renal function, in short-term follow up. The stability of mortality from neoplasms in contrast to other causes over the period 1984-94 largely precludes the possibility that the changes in life expectancy are mainly an artefact, particularly one due to underestimation of the population. To assess the quality of life, we applied the MRS-menopause rating scale.

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Calculations were made on measurements of pressure made in vivo. Agents such as ceftazidime, imipenem and, more recently, meropenem and tazobactam have been used successfully as monotherapy. The balance performance was evaluated using a set of clinical tests including steady stance tests (eyes in opened and closed positions, feet apart, feet together, stride stance, tandem stance and single stance), self-generated perturbations (functional reach, arm raise and step test), external perturbations, Tinetti-gait and 10 m gait time tests.

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Location of the cooperative melting regions in bacteriophage fd DNA. A standing lateral lumbar radiograph is routinely obtained from patients with back pain and/or a disability. Clinical value of the determination of serum calcium with complexons Efficiency of reconstitution of the membrane-associated sn-glycerol 3-phosphate acyltransferase of Escherichia coli. Insulin infusion had no significant effect on the amount of glucose which needed to be infused for maintaining a constant plasma glucose during rest, but there was a large and significant difference in the need for infused glucose during exercise with and without insulin infusion.

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To test this hypothesis, we designed a microcosm experiment in which we grew ponderosa pine, sitka spruce, and western hemlock in forest soil. Genome-wide association: which do you want first: the good news, the bad news, or the good news? One interpretation of this finding is that there is a high degree of periodicity in the position of methionines of, at the very least, the light meromyosin region. Trained interviewers used a questionnaire to identify risk factors for infection (socioeconomic, sanitation and hygiene variables) and collected stool samples from each child for parasitological tests.

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Total protein concentration and total bacterial load as measures of residual interproximal plaque in comparative clinical trials. These competing, concentration-dependent effects of methamphetamine suggest a mechanistic interplay by which lower concentrations of methamphetamine can overcome autoreceptor-mediated inhibition at the soma to increase phasic dopamine transmission.

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The radium-equivalent activity (Raeq) of the samples was calculated and compared with similar data reported in the literature. The study comprised 37 children (22 boys and 15 girls) aged between 4 and 18 years (mean 12 years and 6 months) with chronic hepatitis C, diagnosed on the basis of serological, virological and histological criteria. In vitro cultivation of the histotrophic stages of Haemonchus contortus and Ostertagia spp. Long-term results and prognostic factors of gastric cancer patients with only positive peritoneal lavage cytology. The kinetics of PE2I in healthy volunteers and PD patients were rapid, and the Logan graphical method allowed quantification of distribution volume ratio (DVR) in the caudate nucleus and putamen.

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Insulin is a potent, reversible inhibitor of proliferation in Cloudman S91 mouse melanoma cells. It is exceptional in children in whom rosacea is in itself rare.

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That trend appears to continue as a result of the growing products in commerce using nanotechnology, that is, 5-fold growth in number of countries with nanomaterials research centers. Factor Xa activity gave a positive correlation with prothrombin times of patients receiving warfarin therapy. In this study, a modified method of using solvents for extraction of PLs from dairy matrices was also investigated. Significant cytotoxicity for HMy2 cells, measured by leakage of cytosolic LDH, was also observed for the IT at a concentration of 60 pmol/10(4) cells.

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However, not all meniscus tears are repairable, especially if considerable damage has occurred. Faculty reported noticing positive results to their professional development as well. Annual, targeted larviciding campaigns appear to have been effective and cost-effective medium-term interventions to reduce the epidemiologic and economic burden of dengue in urban areas of Cambodia.

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Antibody staining in the cerebellum was complex, with staining observed primarily in posterior lobes and considerably lower amounts of staining observed in anterior lobes. Uncontrolled activity of the extracytoplasmic function sigma factor sigmaU blocks the process of aerial mycelium formation in this organism. Phylogenetic analysis of the cagE gene indicated that most Japanese isolates formed a different cluster from strains isolated in the West with an association with the vacA genotype.

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Feeling the strain: predicting the third dimension of core affect. Other agents such as vinorelbine, ifosfamide, thymetaq, trimetrexate, gemcitabine and topotecan showed variable activity in patients with SCCHN, but their role is still questionable. American Family Physician has prohibited using editorialists with industry ties for over 20 years. Multilevel analyses were used to estimate and partition the variance in use of androgen deprivation therapy within 6 months of diagnosis between patient or tumor characteristics and urologist to examine the relative contribution of each component to androgen deprivation therapy. Therefore, significant changes in the pattern of sleep occurred during pregnancy in rats, suggesting that the animal model may contribute to understanding the mechanism of sleep disorders related to human pregnancy.